A review of cancer genetics and genomics studies in Africa
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …
Next-generation sequencing and triple-negative breast cancer: insights and applications
D Tierno, G Grassi, S Scomersi, M Bortul… - International Journal of …, 2023 - mdpi.com
The poor survival of triple-negative breast cancer (TNBC) is due to its aggressive behavior,
large heterogeneity, and high risk of recurrence. A comprehensive molecular investigation of …
large heterogeneity, and high risk of recurrence. A comprehensive molecular investigation of …
Distribution of molecular breast cancer subtypes among Algerian women and correlation with clinical and tumor characteristics: a population-based study
F Cherbal, H Gaceb, C Mehemmai, I Saiah… - Breast …, 2015 - content.iospress.com
BACKGROUND: Breast cancer is currently the leading cause of cancer morbidity and
mortality among Algerian women. Molecular classification of breast cancer is an important …
mortality among Algerian women. Molecular classification of breast cancer is an important …
Novel and recurrent BRCA1/BRCA2 germline mutations in patients with breast/ovarian cancer: a series from the south of Tunisia
D Ben Ayed-Guerfali, W Ben Kridis-Rejab… - Journal of Translational …, 2021 - Springer
Background The incidence of breast cancer (BC) and/or ovarian cancer (OC) is increasing in
Tunisia especially in young women and mostly those with family history. However, the …
Tunisia especially in young women and mostly those with family history. However, the …
Breast cancer in East Africa: Prevalence and spectrum of germline SNV/indel and CNVs in BRCA1 and BRCA2 genes among breast cancer patients in Tanzania
LP Rweyemamu, BK Gültaşlar, G Akan… - Cancer …, 2023 - Wiley Online Library
Background Growing prevalence and aggressiveness of breast cancer (BC) among East
African women strongly indicate that the genetic risk factor implicated in the etiology of the …
African women strongly indicate that the genetic risk factor implicated in the etiology of the …
Recurrent mutations of BRCA1, BRCA2 and PALB2 in the population of breast and ovarian cancer patients in Southern Poland
P Wojcik, M Jasiówka, E Strycharz, M Sobol… - Hereditary cancer in …, 2016 - Springer
Background Mutations in the BRCA1, BRCA2 and PALB2 genes are well-established risk
factors for the development of breast and/or ovarian cancer. The frequency and spectrum of …
factors for the development of breast and/or ovarian cancer. The frequency and spectrum of …
Contribution of BRCA1 and BRCA2 germline mutations to early onset breast cancer: a series from north of Morocco
J Bakkach, M Mansouri, T Derkaoui, A Loudiyi… - BMC cancer, 2020 - Springer
Background To date, the contribution of BRCA1/2 mutations in Moroccan early onset breast
cancer patients remains unknown. Here we assess these genetic alterations for the first time …
cancer patients remains unknown. Here we assess these genetic alterations for the first time …
[HTML][HTML] Tracing ovarian cancer research in Morocco: a bibliometric analysis
K El Bairi, O Al Jarroudi, S Afqir - Gynecologic Oncology Reports, 2021 - Elsevier
Background The burden of ovarian cancer (OC) in low-income countries continues to
increase annually. This gynecological cancer, known for its poor survival outcomes, has not …
increase annually. This gynecological cancer, known for its poor survival outcomes, has not …
[HTML][HTML] BRCA1 c. 68_69delAG (exon2), c. 181T> G (exon5), c. 798_799delTT and 943ins10 (exon11) mutations in Burkina Faso
The worldwide variation of BRCA mutations is well known. The c. 68_69delAG, c. 181T> G,
c. 798_799delTT mutations in BRCA1 were observed in Moroccan, Algerian and Tunisian …
c. 798_799delTT mutations in BRCA1 were observed in Moroccan, Algerian and Tunisian …
BRCA1 and BRCA2 Germline Mutation Analysis in Hereditary Breast/Ovarian Cancer Families from the Aures Region (Eastern Algeria): First Report
C Mehemmai, F Cherbal, Y Hamdi, A Guedioura… - Pathology & Oncology …, 2020 - Springer
Breast cancer is currently the leading cause of cancer morbidity and mortality among
Algerian women. In this study, we aimed to investigate the mutation spectrum of BRCA1 and …
Algerian women. In this study, we aimed to investigate the mutation spectrum of BRCA1 and …