The recent successful application of lipid-based nanoparticles as delivery vehicles in COVID-
19 vaccines demonstrated the superior potential of nanoparticle-based technology for …

Amphotericin B (AmB), a broad-spectrum polyene antibiotic in the clinic for more than fifty
years, remains the gold standard in the treatment of life-threatening invasive fungal …

Human fungal diseases differ fundamentally from other infections in diverse ways. As
eukaryotic pathogens, fungi share many similarities with their host cells, which impairs the …

Invasive fungal infections (IFIs) represent a growing public concern for clinicians to manage
in many medical settings, with substantial associated morbidities and mortalities. Among …

Background Amphotericin B (AmB) as a liposomal formulation of AmBisome is the first line of
treatment for the disease, visceral leishmaniasis, caused by the parasite Leishmania …

Introduction Antifungal resistance (AFR) is a growing global public health concern. Little is
currently known about knowledge, attitudes and practices regarding AFR and antifungal …

Fungal infections are a major public health problem resulting from the lack of public policies
addressing these diseases, toxic and/or expensive therapeutic tools, scarce diagnostic tests …

The human diseases caused by the fungal pathogens Cryptococcus neoformans and
Cryptococcus gattii are associated with high indices of mortality and toxic and/or cost …

Cryptococcosis, an invasive mycosis caused by Cryptococcus spp, kills between 20% and
70% of the patients who develop it. There are no vaccines for prevention, and treatment is …

Objective To investigate the in vitro activity, synergism, cytotoxicity and cellular
immunological response, as well as the molecular affinity between amphotericin B (AmB) …