Hearing loss and brain plasticity: the hyperactivity phenomenon

B Herrmann, BE Butler - Brain Structure and Function, 2021 - Springer
Many aging adults experience some form of hearing problems that may arise from auditory
peripheral damage. However, it has been increasingly acknowledged that hearing loss is …

Age-related changes in neural coding of envelope cues: peripheral declines and central compensation

A Parthasarathy, EL Bartlett, SG Kujawa - Neuroscience, 2019 - Elsevier
Aging listeners often experience difficulties in perceiving temporally complex acoustic cues
in noisy environments. These difficulties likely have neurophysiological contributors from …

Synaptopathy in the aging cochlea: Characterizing early-neural deficits in auditory temporal envelope processing

A Parthasarathy, SG Kujawa - Journal of Neuroscience, 2018 - Soc Neuroscience
Aging listeners, even in the absence of overt hearing loss measured as changes in hearing
thresholds, often experience impairments processing temporally complex sounds such as …

Effects of sensorineural hearing loss on cortical synchronization to competing speech during selective attention

SA Fuglsang, J Märcher-Rørsted, T Dau… - Journal of …, 2020 - Soc Neuroscience
When selectively attending to a speech stream in multi-talker scenarios, low-frequency
cortical activity is known to synchronize selectively to fluctuations in the attended speech …

Bottom-up and top-down neural signatures of disordered multi-talker speech perception in adults with normal hearing

A Parthasarathy, KE Hancock, K Bennett, V DeGruttola… - Elife, 2020 - elifesciences.org
In social settings, speech waveforms from nearby speakers mix together in our ear canals.
Normally, the brain unmixes the attended speech stream from the chorus of background …

Enhancing the sensitivity of the envelope-following response for cochlear synaptopathy screening in humans: The role of stimulus envelope

V Vasilkov, M Garrett, M Mauermann, S Verhulst - Hearing Research, 2021 - Elsevier
Auditory de-afferentation, a permanent reduction in the number of inner-hair-cells and
auditory-nerve synapses due to cochlear damage or synaptopathy, can reliably be …

Objective evidence of temporal processing deficits in older adults

S Anderson, H Karawani - Hearing research, 2020 - Elsevier
The older listener's ability to understand speech in challenging environments may be
affected by impaired temporal processing. This review summarizes objective evidence of …

[HTML][HTML] Suppressing fear in the presence of a safety cue requires infralimbic cortical signaling to central amygdala

K Ng, M Pollock, A Escobedo, B Bachman… - …, 2024 - nature.com
Stressful events can have lasting and impactful effects on behavior, especially by disrupting
normal regulation of fear and reward processing. Accurate discrimination among …

Neural signatures of temporal regularity processing in sounds differ between younger and older adults

B Herrmann, C Buckland, IS Johnsrude - Neurobiology of Aging, 2019 - Elsevier
Sensitivity to temporal regularity (eg, recurring modulation in amplitude) is crucial for speech
perception. Degradation of the auditory periphery due to aging and hearing loss may lead to …

[HTML][HTML] Individual differences in the attentional modulation of the human auditory brainstem response to speech inform on speech-in-noise deficits

M Saiz-Alía, AE Forte, T Reichenbach - Scientific Reports, 2019 - nature.com
People with normal hearing thresholds can nonetheless have difficulty with understanding
speech in noisy backgrounds. The origins of such supra-threshold hearing deficits remain …