[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism

Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

The protective role of resveratrol in diabetic wound healing

M Bi, Y Qin, L Wang, J Zhang - Phytotherapy Research, 2023 - Wiley Online Library
Diabetic wounds are severe complications of diabetes mellitus (DM), which have difficulty in
healing. Although diverse treatments have been used, the prognosis of diabetic wounds is …

[HTML][HTML] Diabetes mellitus and risk of breast cancer: a large-scale, prospective, population-based study

F Xiong, J Wang, JL Nierenberg… - British Journal of …, 2023 - nature.com
Background The objective of this study was to evaluate associations of diabetes overall, type
1 diabetes (T1D), and type 2 diabetes (T2D) with breast cancer (BCa) risk. Methods We …

[HTML][HTML] PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK …

Z Ma, Y Ding, X Ding, H Mou, R Mo, Q Tan - Cell Death Discovery, 2023 - nature.com
During the process of wound healing, fibroblasts migrate to the wound site and perform
essential functions in promoting cell proliferation, as well as synthesizing and secreting the …

PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF‐1α protein stability and gene expression

Z Ma, R Mo, P Yang, Y Ding, H Zhang… - The FASEB …, 2023 - Wiley Online Library
Fibroblast activation disorder is one of the main pathogenic characteristics of diabetic
wounds. Orchestrated fibroblast functions and myofibroblast differentiation are crucial for …

Development and characterization of polydeoxyribonucleotide (PDRN) loaded chitosan polyplex: In vitro and in vivo evaluation of wound healing activity

SHS Dananjaya, KGP Madushani, J Dilrukshi… - International Journal of …, 2023 - Elsevier
Polydeoxyribonucleotide (PDRN) is an accelerated diabetic wound healing therapy with
promising abilities to promote cell growth, angiogenesis, collagen synthesis, and reduce …

The inhibitory mechanism of amylase inhibitors and research progress in nanoparticle-based inhibitors

Q Lin, C Qiu, X Li, S Sang, DJ McClements… - Critical Reviews in …, 2023 - Taylor & Francis
Type 2 diabetes is caused by persistently high blood sugar levels, which leads to metabolic
dysregulation and an increase in the risk of chronic diseases such as diabetes and obesity …

[PDF][PDF] Platelet Dysfunction in Diabetes Mellitus

FU Onuigwe, H Ambi, NJ Uchechukwu… - Elite Journal of …, 2024 - researchgate.net
Platelet dysfunction in diabetes mellitus is a multifaceted issue with significant implications
for vascular health. The interplay of hyperglycemia, oxidative stress, abnormal lipid profiles …

Defining Spatial Epidemiology: A Systematic Review and Re-Orientation

CN Morrison, CF Mair, L Bates, DT Duncan… - …, 2024 - journals.lww.com
Background. Spatial epidemiology has emerged as an important subfield of epidemiology
over the past quarter century. We trace the origins of spatial epidemiology and note that its …

[HTML][HTML] The capacity of exosomes derived from adipose-derived stem cells to enhance wound healing in diabetes

F Cai, W Chen, R Zhao, Y Liu - Frontiers in Pharmacology, 2023 - frontiersin.org
The slow healing and nonhealing of diabetic wounds have long posed challenges for
clinical practitioners. In the presence of elevated glucose levels, the body's regulatory …