Synthetic organic electrosynthesis has grown in the past few decades by achieving many
valuable transformations for synthetic chemists. Although electrocatalysis has been popular …

Alkene-derived radical cations are versatile reactive intermediates and have been widely
applied in the construction of complex functionalized molecules and cyclic systems for …

Hydroamination, the addition of an N–H bond across a C–C multiple bond, is a reaction with
a great synthetic potential. Important advances have been made in the last decades …

Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …

Azetidines are prominent structural scaffolds in bioactive molecules, medicinal chemistry,
and ligand design for transition metals. However, state-of-the-art methods cannot be applied …

Following a strong regain of interest over the past 20 years in the chemistry of allenes, this
“forgotten” family of unsaturated molecules is undergoing a renaissance. In this context, the …

Conventional methods for carrying out carbon–hydrogen functionalization and carbon–
nitrogen bond formation are typically conducted at elevated temperatures, and rely on …

Nitrogen (N) is ubiquitously found in bioactive molecules, pharmaceutical agents, and
organic functional materials. Accordingly, development of new C–N bond-forming catalysis …

Metal-catalyzed highly Markovnikov-type selective hydrofunctionalization of terminal alkynes
provides a straightforward and atom-economical route to access 1, 1-disubstituted alkenes …

Hexafluoroisopropanol (HFIP) is a solvent with unique properties that has recently gained
attention for promoting a wide range of challenging chemical reactions. It was initially …