DNA damage in preimplantation embryos and gametes: specification, clinical relevance and repair strategies

R Musson, Ł Gąsior, S Bisogno… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND DNA damage is a hazard that affects all cells of the body. DNA-damage
repair (DDR) mechanisms are in place to repair damage and restore cellular function, as are …

State-of-the-art and future perspectives in infertility diagnosis: conventional versus nanotechnology-based assays

BA Andone, IM Handrea-Dragan, I Botiz… - … , Biology and Medicine, 2023 - Elsevier
According to the latest World Health Organization statistics, around 50 to 80 million people
worldwide suffer from infertility, amongst which male factors are responsible for around 20 to …

Embryo morphokinetics derived from fresh and vitrified bovine oocytes predict blastocyst development and nuclear abnormalities

D Angel-Velez, T De Coster, N Azari-Dolatabad… - Scientific Reports, 2023 - nature.com
Embryo development is a dynamic process and critical stages may go unnoticed with the
use of traditional morphologic assessments, especially the timing of embryonic divisions and …

Morphological, biochemical and functional studies to evaluate bovine oocyte vitrification

C Gutnisky, S Morado, T Gadze, A Donato, G Alvarez… - Theriogenology, 2020 - Elsevier
The aim of the present study was to evaluate the effect of vitrification on morphological,
biochemical and functional parameters of matured bovine oocytes at different recovery …

Serum albumin concentration of donor cows as an indicator of developmental competence of oocytes

MP Smuts, S De Bruyn, PN Thompson, DE Holm - Theriogenology, 2019 - Elsevier
Adequate nutrition is required for maintenance of normal reproduction in cattle. Albumin, the
best marker and fundamental part of nutrition, most abundant plasma protein and major …

The walnut-derived peptide TW-7 improves mouse parthenogenetic embryo development of vitrified MII oocytes potentially by promoting histone lactylation

Y Wei, B Pan, J Qin, B Cao, T Lv, J Ye, A Ning… - Journal of Animal …, 2024 - Springer
Background Previous studies have shown that the vitrification of metaphase II (MII) oocytes
significantly represses their developmental potential. Abnormally increased oxidative stress …

Distribution of tetraspanins in bovine ovarian tissue and fresh/vitrified oocytes

J Jankovičová, P Sečová, Ľ Horovská… - Histochemistry and cell …, 2023 - Springer
Tetraspanin proteins are mostly known as organizers of molecular complexes on cell
membranes, widely expressed on the surface of most nucleated cells. Although tetraspanins …

Ex ovo omniawhy don't we know more about egg quality via imaging?

CF Boylan, KM Sambo, G Neal-Perry… - Biology of …, 2024 - academic.oup.com
Determining egg quality is the foremost challenge in assisted reproductive technology
(ART). Although extensive advances have been made in multiple areas of ART over the last …

In Vitro Fertilization in Kazakh Whiteheaded Cattle: A Comparative Study

B Seisenov, D Duimbayev, N Kazhgaliyev… - Life, 2023 - mdpi.com
In vitro fertilization (IVF) technologies have great potential in the preservation of endangered
species. In the current study, an IVF experiment was carried out to evaluate whether …

Effect of vitrification of in vitro matured prepubertal goat oocytes on embryo development after parthenogenic activation and intracytoplasmic sperm injection

I Menéndez-Blanco, S Soto-Heras, MG Catalá… - Cryobiology, 2020 - Elsevier
This work studies the effect of vitrification of in vitro matured (IVM) prepubertal goat oocytes
on: 1) oocyte damage assessed by reactive oxygen species (ROS) level and apoptosis and …