The role of B cells in the pathogenesis of systemic sclerosis: an update
LI Sakkas, CG Katsiari, D Daoussis… - Rheumatology, 2023 - academic.oup.com
The pathogenesis of SSc is incompletely understood, but several lines of evidence suggest
that B cells are involved. Effector B (Beff) cells are hyperactivated and produce …
that B cells are involved. Effector B (Beff) cells are hyperactivated and produce …
Lymphocyte depleting and modulating therapies for chronic lung allograft dysfunction
S Bos, P Pradère, H Beeckmans, A Zajacova… - Pharmacological …, 2023 - Elsevier
Chronic lung rejection, also called chronic lung allograft dysfunction (CLAD), remains the
major hurdle limiting long-term survival after lung transplantation, and limited therapeutic …
major hurdle limiting long-term survival after lung transplantation, and limited therapeutic …
[HTML][HTML] Ibrutinib in steroid-refractory chronic graft-versus-host disease, a single-center experience
Chronic graft-versus-host disease (cGVHD) is a leading cause of late morbidity and mortality
after allogenic hematopoietic stem cell transplantation. Corticosteroid-based therapies are a …
after allogenic hematopoietic stem cell transplantation. Corticosteroid-based therapies are a …
An open‐label study of belumosudil, a selective ROCK2 inhibitor, as second or subsequent line of therapy for steroid‐dependent/steroid‐resistant chronic GVHD
Y Inamoto, K Kato, T Kawakita, Y Onishi… - American Journal of …, 2024 - Wiley Online Library
Belumosudil mesylate is a selective Rho‐associated coiled‐coil kinase 2 inhibitor with
immunomodulatory and antifibrosis effects. This multicenter, open‐label, single‐arm study …
immunomodulatory and antifibrosis effects. This multicenter, open‐label, single‐arm study …
Novel Pharmacological Treatment Options of Steroid‐Refractory Graft‐versus‐Host Disease
I Kovalenko, T Saleem, M Shah… - Advances in …, 2023 - Wiley Online Library
Background. Graft‐versus‐host disease (GVHD) is a potentially fatal complication of
allogeneic hematopoietic stem cell transplant. The mainstay of treatment is corticosteroids …
allogeneic hematopoietic stem cell transplant. The mainstay of treatment is corticosteroids …
ERS/EBMT clinical practice guidelines on treatment of pulmonary chronic graft-versus-host disease in adults
S Bos, J Murray, M Marchetti, GS Cheng… - European …, 2024 - Eur Respiratory Soc
Chronic graft-versus-host disease (cGvHD) is a common complication after allogeneic
haematopoietic stem cell transplantation, characterised by a broad disease spectrum that …
haematopoietic stem cell transplantation, characterised by a broad disease spectrum that …
[HTML][HTML] Oral Chronic Graft-Versus-Host Disease: Pathogenesis, Diagnosis, Current Treatment, and Emerging Therapies
JT Nguyen, M Jessri, AC Costa-da-Silva… - International Journal of …, 2024 - mdpi.com
Chronic graft-versus-host disease (cGvHD) is a multisystem disorder that occurs in
recipients of allogeneic hematopoietic (alloHCT) stem cell transplants and is characterized …
recipients of allogeneic hematopoietic (alloHCT) stem cell transplants and is characterized …
Effectiveness of Ibrutinib in the Management of Chronic GVHD
Objectives Chronic graft-versus-host disease (cGVHD) represents a significant adverse
event that may ensue following allogeneic hematopoietic stem cell transplantation (Allo …
event that may ensue following allogeneic hematopoietic stem cell transplantation (Allo …
Clinical features of non-infectious pulmonary complications after donor lymphocyte infusion in post-transplant patients: The Nagasaki Transplant Group Experience
M Fujioka, H Itonaga, T Furumoto, C Sakaki… - Transplant …, 2022 - Elsevier
Donor lymphocyte infusion (DLI) is a therapeutic modality for relapsed hematological
malignancies after allogeneic hematopoietic stem cell transplantation. We retrospectively …
malignancies after allogeneic hematopoietic stem cell transplantation. We retrospectively …
[HTML][HTML] Efficacy and Safety of Ibrutinib for Chronic Graft-Versus-Host Disease: A Systematic Review
D Santosa, D Rizky, K Tandarto, I Kartiyani… - Asian Pacific Journal …, 2023 - ncbi.nlm.nih.gov
Method: We incorporated search engines from PubMed, Embase, Cochrane Library,
Scopus, Web of Science, and ClinicalTrials. gov. The study was performed following the …
Scopus, Web of Science, and ClinicalTrials. gov. The study was performed following the …