Ferroptosis: Promising approach for cancer and cancer immunotherapy
S Zheng, XY Guan - Cancer Letters, 2023 - Elsevier
Ferroptosis is the cell death induced by ferrous ions and lipid peroxidation accumulation in
tumor cells. Targeting ferroptosis, which is regulated by various metabolic and immune …
tumor cells. Targeting ferroptosis, which is regulated by various metabolic and immune …
Role of lipoproteins in the pathophysiology of breast cancer
Breast cancer is one of the most common malignancies in women and the leading cause of
cancer mortality. Hypercholesterolemia and obesity are potential risk factors for the …
cancer mortality. Hypercholesterolemia and obesity are potential risk factors for the …
Depletion of Labile Iron Induces Replication Stress and Enhances Responses to Chemoradiation in Non-Small-Cell Lung Cancer
K Bayanbold, M Singhania, MA Fath, CC Searby… - Antioxidants, 2023 - mdpi.com
The intracellular redox-active labile iron pool (LIP) is weakly chelated and available for
integration into the iron metalloproteins that are involved in diverse cellular processes …
integration into the iron metalloproteins that are involved in diverse cellular processes …
Ferroptosis: new insight into the mechanisms of diabetic nephropathy and retinopathy
L Li, Y Dai, D Ke, J Liu, P Chen, D Wei… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are the most serious and common
diabetes-associated complications. DN and DR are all highly prevalent and dangerous …
diabetes-associated complications. DN and DR are all highly prevalent and dangerous …
Design, Synthesis and Cytotoxicity Screening of New Thiazole Derivatives as Potential Anticancer Agents through VEGFR-2 Inhibition
Z-configurated isomers are kinetically preferred molecules. Compounds with Z-configuration
are contained in many natural products, biologically active compounds and as synthons for …
are contained in many natural products, biologically active compounds and as synthons for …
Polysaccharide of Atractylodes macrocephala Koidz Alleviates Cyclophosphamide-Induced Thymus Ferroptosis in Gosling
X Zhou, N Cao, D Xu, Y Tian, X Shen, D Jiang… - Animals, 2022 - mdpi.com
Simple Summary During the brooding stage, the goslings are susceptible to various
stresses, damaging the thymus and decreasing immune function. Ferroptosis is cell death …
stresses, damaging the thymus and decreasing immune function. Ferroptosis is cell death …
Ferroptosis contributes to cyclophosphamide-induced hemorrhagic cystitis
Z Mao, K Zhong, X Liu, X Zeng - Chemico-Biological Interactions, 2023 - Elsevier
Cyclophosphamide (CYP) is extensively used in tumor therapy, but its clinical application is
limited by its toxic effects on the bladder. Since CYP-induced cystitis is believed to be …
limited by its toxic effects on the bladder. Since CYP-induced cystitis is believed to be …
Ferroptosis: A novel therapeutic strategy and mechanism of action in glioma
G Zhang, Y Fang, X Li, Z Zhang - Frontiers in oncology, 2022 - frontiersin.org
Glioma is the most common malignant tumor of the central nervous system and resistance is
easily developed to chemotherapy drugs during the treatment process, resulting in high …
easily developed to chemotherapy drugs during the treatment process, resulting in high …
Polyherbal formulation conjugated to gold nanoparticles induced ferroptosis in drug-resistant breast cancer stem cells through ferritin degradation
P Chittineedi, A Mohammed… - Frontiers in …, 2023 - frontiersin.org
Aim: Due to their minimal side effects, the anti-cancer properties of the polyherbal
formulation are being investigated. However, due to their low absorption potential, the …
formulation are being investigated. However, due to their low absorption potential, the …
Aqueous Nyctanthes arbortristis and doxorubicin conjugated gold nanoparticles synergistically induced mTOR-dependent autophagy-mediated ferritinophagy in …
P Chittineedi, SL Pandrangi… - Frontiers in …, 2023 - frontiersin.org
Aim: Nyctanthes arbortristis Linn is a potential anti-diabetic drug that reduces glucose levels
by delaying carbohydrate digestion. The tumor microenvironment is characterized by …
by delaying carbohydrate digestion. The tumor microenvironment is characterized by …