Qualitative sex differences in pain processing: emerging evidence of a biased literature

JS Mogil - Nature Reviews Neuroscience, 2020 - nature.com
Although most patients with chronic pain are women, the preclinical literature regarding pain
processing and the pathophysiology of chronic pain has historically been derived …

[HTML][HTML] Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain

V Arora, JN Campbell, MK Chung - Pharmacology & therapeutics, 2021 - Elsevier
Capsaicin, the pungent ingredient in chili peppers, produces intense burning pain in
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …

[HTML][HTML] Neurobiological mechanisms of TENS-induced analgesia

WW Peng, ZY Tang, FR Zhang, H Li, YZ Kong… - Neuroimage, 2019 - Elsevier
Pain inhibition by additional somatosensory input is the rationale for the widespread use of
Transcutaneous Electrical Nerve Stimulation (TENS) to relieve pain. Two main types of …

[HTML][HTML] Neuroimaging of pain in animal models: a review of recent literature

JT Da Silva, DA Seminowicz - Pain reports, 2019 - journals.lww.com
Neuroimaging of pain in animals allows us to better understand mechanisms of pain
processing and modulation. In this review, we discuss recently published brain imaging …

[PDF][PDF] Effects of exercise-induced hypoalgesia and its neural mechanisms

B Wu, L Zhou, C Chen, J Wang, LI Hu… - Medicine & Science in …, 2022 - researchgate.net
MATERIALS AND METHODS Participants. A total of 48 participants (24 females; mean±SD
age, 23.5±2.3 yr) were recruited from Shanghai University of Sport through advertisements …

CGRP monoclonal antibody prevents the loss of diffuse noxious inhibitory controls (DNIC) in a mouse model of post-traumatic headache

CM Kopruszinski, JM Turnes, J Swiokla… - …, 2021 - journals.sagepub.com
Aim Determine the role of calcitonin-gene related peptide in promoting post-traumatic
headache and dysregulation of central pain modulation induced by mild traumatic brain …

Introducing descending control of nociception: a measure of diffuse noxious inhibitory controls in conscious animals

K Bannister, MW Kucharczyk, T Graven-Nielsen… - Pain, 2021 - journals.lww.com
Ever since Le Bars et al. 21 detailed in 1979 that “the activity of convergent dorsal horn
neurons could be powerfully inhibited by noxious stimuli applied to various parts of the …

Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice

W Nemoto, D Kozak, SG Sotocinal, S Tansley… - Pain, 2023 - journals.lww.com
Descending control of nociception (DCN; also known as conditioned pain modulation [CPM],
the behavioral correlate of diffuse noxious inhibitory controls) is the phenomenon whereby …

Age and sex differences in acute and osteoarthritis-like pain responses in rats

JY Ro, Y Zhang, C Tricou, D Yang… - The Journals of …, 2020 - academic.oup.com
In this study, we investigated age and sex differences in acute and chronic pain in rats.
Groups of young (3–6 months) and aged (20–24 months) male and female Fischer 344 rats …

Individual variability and sex differences in conditioned pain modulation and the impact of resilience, and conditioning stimulus pain unpleasantness and salience

S Firouzian, NR Osborne, JC Cheng, JA Kim… - Pain, 2020 - journals.lww.com
Distinct pain experiences are shaped both by personal attributes and characteristics of
noxious stimuli. An Individual's capacity for endogenous pain inhibition (reflected by …