Bacterial inclusion bodies (IBs) are functional, non-toxic amyloids occurring in recombinant
bacteria showing analogies with secretory granules of the mammalian endocrine system …

Many protein species produced in recombinant bacteria aggregate as insoluble protein
clusters named inclusion bodies (IBs). IBs are discarded from further processing or are …

Understanding the structure, functionalities and biology of functional amyloids is an issue of
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …

The bacterium Escherichia coli is a major host for recombinant protein production of non-
glycosylated products. Depending on the expression strategy, the recombinant protein can …

Bacterial inclusion bodies (IBs) consist of unfolded protein aggregates and represent
inactive waste products often accumulating during heterologous overexpression of …

The development of innovative medicines and personalized biomedical approaches require
the identification and implementation of new biocompatible materials produced by …

In the last decades, the understanding of inclusion body biology and consequently, of their
properties and potential biotechnological applications have dramatically changed …

Background Bacterial inclusion bodies are submicron protein clusters usually found in
recombinant bacteria that have been traditionally considered as undesirable products from …

Background The bacterium E. coli is a major host for recombinant protein production of non-
glycosylated products. Depending on the expression strategy, the recombinant protein can …

Proteins are synthesized in heterologous systems because of the impossibility to obtain
satisfactory yields from natural sources. The production of soluble and functional …