Toll-like receptor signaling pathways

T Kawasaki, T Kawai - Frontiers in immunology, 2014 - frontiersin.org
Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing
pathogen-associated molecular patterns derived from various microbes. TLRs signal …

Cytokine tuning of intestinal epithelial function

C Andrews, MH McLean, SK Durum - Frontiers in immunology, 2018 - frontiersin.org
The intestine serves as both our largest single barrier to the external environment and the
host of more immune cells than any other location in our bodies. Separating these potential …

Antibiotic adjuvants: diverse strategies for controlling drug‐resistant pathogens

EE Gill, OL Franco… - Chemical biology & drug …, 2015 - Wiley Online Library
The growing number of bacterial pathogens that are resistant to numerous antibiotics is a
cause for concern around the globe. There have been no new broad‐spectrum antibiotics …

Toll-like receptor 9 agonists in cancer

L Karapetyan, JJ Luke, D Davar - OncoTargets and therapy, 2020 - Taylor & Francis
Abstract Toll-like receptor 9 (TLR9) is a pattern recognition receptor that is predominantly
located intracellularly in immune cells, including dendritic cells, macrophages, natural killer …

Toll-like receptors in the vascular system: sensing the dangers within

S Goulopoulou, CG McCarthy, RC Webb - Pharmacological reviews, 2016 - ASPET
Toll-like receptors (TLRs) are components of the innate immune system that respond to
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …

TLR-dependent human mucosal epithelial cell responses to microbial pathogens

R McClure, P Massari - Frontiers in immunology, 2014 - frontiersin.org
Toll-like receptor (TLR) signaling represents one of the best studied pathways to implement
defense mechanisms against invading microbes in human being as well as in animals …

Human TLR10 is an anti-inflammatory pattern-recognition receptor

M Oosting, SC Cheng, JM Bolscher… - Proceedings of the …, 2014 - National Acad Sciences
Toll-like receptor (TLR) 10 is the only pattern-recognition receptor without known ligand
specificity and biological function. We demonstrate that TLR10 is a modulatory receptor with …

Listeria adhesion protein induces intestinal epithelial barrier dysfunction for bacterial translocation

R Drolia, S Tenguria, AC Durkes, JR Turner… - Cell host & …, 2018 - cell.com
Intestinal epithelial cells are the first line of defense against enteric pathogens, yet bacterial
pathogens, such as Listeria monocytogenes, can breach this barrier. We show that Listeria …

The porcine innate immune system: an update

KH Mair, C Sedlak, T Käser, A Pasternak… - Developmental & …, 2014 - Elsevier
Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …

[图书][B] Molecular medical microbiology

M Sussman - 2023 - books.google.com
Molecular Medical Microbiology, Third Edition presents the latest release in what is
considered to be the first book to synthesize new developments in both molecular and …