The 'fractionable autism triad': a review of evidence from behavioural, genetic, cognitive and neural research

F Happé, A Ronald - Neuropsychology review, 2008 - Springer
Autism is diagnosed on the basis of a triad of impairments in social interaction,
communication, and flexible imaginative functions (with restricted and repetitive behaviors …

Autism: The phenotype in relatives

A Bailey, S Palferman, L Heavey… - Journal of autism and …, 1998 - Springer
There is broad agreement that genetic influences are central in the development of
idiopathic autism. Whether relatives manifest genetically related milder phenotypes, and if …

Sex differences in autism spectrum disorder: an examination of developmental functioning, autistic symptoms, and coexisting behavior problems in toddlers

SL Hartley, DM Sikora - Journal of autism and developmental disorders, 2009 - Springer
Little is known about the female presentation of autism spectrum disorder (ASD) during early
childhood. We investigated sex differences in developmental profiles using the Mullen …

Sex differences in children with autism spectrum disorder identified within a high-risk infant cohort

L Zwaigenbaum, SE Bryson, P Szatmari, J Brian… - Journal of autism and …, 2012 - Springer
Sex differences were examined in 3-year-olds with autism spectrum disorders (ASD)
ascertained from a high-risk cohort, and high-and low-risk comparison groups. Participants …

[HTML][HTML] Imprinting, the X-chromosome, and the male brain: explaining sex differences in the liability to autism

DH Skuse - Pediatric research, 2000 - nature.com
Males are at least four times more likely to develop autism than females. Among relatives
with a broader autistic phenotype, males predominate too. Autism is a highly heritable …

Essential versus complex autism: definition of fundamental prognostic subtypes

JH Miles, TN Takahashi, S Bagby… - American journal of …, 2005 - Wiley Online Library
Heterogeneity within the autism diagnosis obscures the genetic basis of the disorder and
impedes our ability to develop effective treatments. We found that by using two readily …

Genetics and child psychiatry: II Empirical research findings

M Rutter, J Silberg, T O'Connor… - The Journal of Child …, 1999 - cambridge.org
Key substantive findings from quantitative and molecular genetic research are reviewed in
relation to affective disorder, schizophrenia, autism, hyperkinetic/attention deficit disorder …

Genetics of autism: overview and new directions

P Szatmari, MB Jones, L Zwaigenbaum… - Journal of autism and …, 1998 - Springer
Genetic epidemiology is the study of inherited factors involved in the etiology of a disease or
disorder and uses the methods of both medical genetics and clinical epidemiology. In …

What is known about autism: genes, brain, and behavior

SL Santangelo, K Tsatsanis - American Journal of Pharmacogenomics, 2005 - Springer
Autism is a neurodevelopmental disorder of genetic origins, with a heritability of about 90%.
Autistic disorder is classed within the broad domain of pervasive developmental disorders …

Epidemiology of autism: Prevalence, associated characteristics, and implications for research and service delivery

SE Bryson, IM Smith - Mental Retardation and Developmental …, 1998 - Wiley Online Library
We provide an overview of research on the epidemiology of autism and related pervasive
developmental disorders (PDDs). First, we provide data on the prevalence of autism, which …