Nanostructured carbon based materials with unique and tunable properties make them to be
utilized for various applications in different forms especially for energy and environmental …

Traditional screening paradigms often focus on single targets. To facilitate drug discovery in
the more complex physiological environment of a cell or organism, powerful cellular imaging …

Several recent studies have suggested that the adult bone marrow harbors cells that can
influence β-cell regeneration in diabetic animals. Other reports, however, have contradicted …

Diabetes is one of the most prevalent, costly, and debilitating diseases in the world.
Although traditional insulin therapy has alleviated the short-term effects, long-term …

Abstract Type 2 diabetes (T2D) is characterized by progressive and inexorable β‑cell
dysfunction, leading to insulin deficiency. Novel strategies to preserve the remaining β‑cells …

Islet replacement is a promising therapy for treating Diabetes Mellitus, but the supply of
donor tissue for transplantation is limited. To overcome this limitation, endocrine tissue can …

Tissue Engineering (TE) is a scientific field mainly focused on the development of tissue and
organ substitutes by controlling biological, biophysical and/or biomechanical parameters in …

Tissue engineering (TE) is an emerging field where alternate/artificial tissues or organ
substitutes are implanted to mimic the functionality of damaged or injured tissues. Earlier …

Neurogenin 3 is necessary for endocrine cell development in the embryonic pancreas and
has been shown to induce transdifferentiation duct cells from adult pancreas toward a neuro …

Aims/hypothesis Impairment of beta cell mass and function is evident in both type 1 and type
2 diabetes. In healthy physiological conditions pancreatic beta cells adapt to the body's …