Computational principles of supervised learning in the cerebellum

JL Raymond, JF Medina - Annual review of neuroscience, 2018 - annualreviews.org
Supervised learning plays a key role in the operation of many biological and artificial neural
networks. Analysis of the computations underlying supervised learning is facilitated by the …

Redefining the cerebellar cortex as an assembly of non-uniform Purkinje cell microcircuits

NL Cerminara, EJ Lang, RV Sillitoe… - Nature Reviews …, 2015 - nature.com
The adult mammalian cerebellar cortex is generally assumed to have a uniform
cytoarchitecture. Differences in cerebellar function are thought to arise primarily through …

Spatiotemporal firing patterns in the cerebellum

CI De Zeeuw, FE Hoebeek, LWJ Bosman… - Nature Reviews …, 2011 - nature.com
Neurons are generally considered to communicate information by increasing or decreasing
their firing rate. However, in principle, they could in addition convey messages by using …

Motor learning and the cerebellum

CI De Zeeuw, MM Ten Brinke - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Although our ability to store semantic declarative information can nowadays be readily
surpassed by that of simple personal computers, our ability to learn and express procedural …

The cerebellar microcircuit as an adaptive filter: experimental and computational evidence

P Dean, J Porrill, CF Ekerot, H Jörntell - Nature Reviews Neuroscience, 2010 - nature.com
Initial investigations of the cerebellar microcircuit inspired the Marr–Albus theoretical
framework of cerebellar function. We review recent developments in the experimental …

The sleeping cerebellum

CB Canto, Y Onuki, B Bruinsma, YD van der Werf… - Trends in …, 2017 - cell.com
We sleep almost one-third of our lives and sleep plays an important role in critical brain
functions like memory formation and consolidation. The role of sleep in cerebellar …

Cerebellar modules and their role as operational cerebellar processing units

R Apps, R Hawkes, S Aoki, F Bengtsson, AM Brown… - The Cerebellum, 2018 - Springer
The compartmentalization of the cerebellum into modules is often used to discuss its
function. What, exactly, can be considered a module, how do they operate, can they be …

Cerebellar climbing fibers encode expected reward size

N Larry, M Yarkoni, A Lixenberg, M Joshua - elife, 2019 - elifesciences.org
Climbing fiber inputs to the cerebellum encode error signals that instruct learning. Recently,
evidence has accumulated to suggest that the cerebellum is also involved in the processing …

Functions of interneurons in mouse cerebellum

NH Barmack, V Yakhnitsa - Journal of Neuroscience, 2008 - Soc Neuroscience
The output signal of Purkinje cells is conveyed by the modulated discharge of simple spikes
(SSs) often ascribed to mossy fiber–granule cell–parallel fiber inputs to Purkinje cell …

Strength and timing of motor responses mediated by rebound firing in the cerebellar nuclei after Purkinje cell activation

L Witter, CB Canto, TM Hoogland… - Frontiers in neural …, 2013 - frontiersin.org
The cerebellum refines the accuracy and timing of motor performance. How it encodes
information to perform these functions is a major topic of interest. We performed whole cell …