Polyphosphates play a crucial role in various biological processes, such as blood
coagulation, energy homeostasis, and cellular stress response. However, their isolation …

Motivation Accurate prediction of RNA subcellular localization plays an important role in
understanding cellular processes and functions. Although post-transcriptional processes are …

The immune system is highly regulated but, when dysregulated, suboptimal protective or
overly robust immune responses can lead to immune-mediated disorders. The genetic and …

Background Portal vein thrombosis (PVT) is a significant issue in cirrhotic patients,
necessitating early detection. This study aims to develop a data-driven predictive model for …

The subcellular compartment-specific molecular interactions (SCSIs) are the building blocks
for most molecular functions, biological processes and disease pathogeneses. Extensive …

The development of a cytosolic delivery strategy for biopharmaceuticals is one of the central
issues in drug development. Knowledge of the mechanisms underlying these processes …

Gene expression is a fundamental and highly regulated process involving a series of tightly
coordinated steps, including transcription, post-transcriptional processing, translation, and …

Genes are the basic units of protein synthesis in organisms, and accurately identifying the
translation initiation site (TIS) of genes is crucial for understanding the regulation …

The precise coordination of important biological processes, such as differentiation and
development, is highly dependent on the regulation of expression of the genetic information …

SUMMARY Tyrosine protein-kinase 2 (TYK2), a member of the Janus kinase family,
mediates inflammatory signaling through multiple cytokines, including interferon-α (IFNα) …