Immune response following traumatic spinal cord injury: Pathophysiology and therapies

RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

[HTML][HTML] The neurobiology of non-coding RNAs and Alzheimer's disease pathogenesis: Pathways, mechanisms and translational opportunities

E Lauretti, K Dabrowski, D Praticò - Ageing Research Reviews, 2021 - Elsevier
In the past two decades, advances in sequencing technology and analysis of the human and
mouse genome have led to the discovery of many non-protein-coding RNAs (ncRNAs) …

Extracellular vesicles as an emerging frontier in spinal cord injury pathobiology and therapy

D Dutta, N Khan, J Wu, SM Jay - Trends in neurosciences, 2021 - cell.com
Extracellular vesicles (EVs) are membrane-delimited particles that are secreted by nearly all
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …

Intranasally administered exosomes from umbilical cord stem cells have preventive neuroprotective effects and contribute to functional recovery after perinatal brain …

G Thomi, M Joerger-Messerli, V Haesler, L Muri… - Cells, 2019 - mdpi.com
Perinatal brain injury (PBI) in preterm birth is associated with substantial injury and
dysmaturation of white and gray matter, and can lead to severe neurodevelopmental deficits …

Exosome therapeutics for lung regenerative medicine

K Popowski, H Lutz, S Hu, A George… - Journal of …, 2020 - Taylor & Francis
Exosomes are 30 to 100 nm extracellular vesicles that are secreted by many cell types.
Initially viewed as cellular garbage with no biological functions, exosomes are now …

miRNA involvement in cerebral ischemia-reperfusion injury

MA Neag, AO Mitre, CC Burlacu, AI Inceu… - Frontiers in …, 2022 - frontiersin.org
Cerebral ischemia reperfusion injury is a debilitating medical condition, currently with only a
limited amount of therapies aimed at protecting the cerebral parenchyma. Micro RNAs …

Neuroprotective effects of human amniotic fluid stem cells-derived secretome in an ischemia/reperfusion model

V Castelli, I Antonucci, M d'Angelo… - Stem cells …, 2021 - academic.oup.com
Stem cells offer the basis for the promotion of robust new therapeutic approaches for a
variety of human disorders. There are still many limitations to be overcome before clinical …

Physical exercise and the functions of microRNAs

JAC Dos Santos, ASC Veras, VRG Batista… - Life sciences, 2022 - Elsevier
MicroRNAs (miRNAs) control RNA translation and are a class of small, tissue-specific, non-
protein-coding RNAs that maintain cellular homeostasis through negative gene regulation …

Astrocyte-derived exosomes carry microRNA-17-5p to protect neonatal rats from hypoxic-ischemic brain damage via inhibiting BNIP-2 expression

L Du, Y Jiang, Y Sun - Neurotoxicology, 2021 - Elsevier
Exosomes play critical roles in neurogenesis. This study aims to explore the mechanism of
astrocyte-derived exosomes in neonatal rats with hypoxic-ischemic brain damage (HIBD) …

The role of microRNAs in neurobiology and pathophysiology of the hippocampus

SK Rashidi, A Kalirad, S Rafie, E Behzad… - Frontiers in molecular …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short non-coding and well-conserved RNAs that are linked to
many aspects of development and disorders. MicroRNAs control the expression of genes …