Human papillomavirus vaccine efficacy and effectiveness against cancer

S Kamolratanakul, P Pitisuttithum - Vaccines, 2021 - mdpi.com
Human papillomavirus (HPV) is the most common sexually transmitted infection, with 15
HPV types related to cervical, anal, oropharyngeal, penile, vulvar, and vaginal cancers …

Chimeric antigen receptor therapy

CH June, M Sadelain - New England Journal of Medicine, 2018 - Mass Medical Soc
Chimeric Antigen Receptor T Cells This review addresses T-cell engineering and synthetic
immunity, with a focus on producing durable remissions in patients with treatment-refractory …

Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income …

M Brisson, JJ Kim, K Canfell, M Drolet, G Gingras… - The Lancet, 2020 - thelancet.com
Summary Background The WHO Director-General has issued a call for action to eliminate
cervical cancer as a public health problem. To help inform global efforts, we modelled …

Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16–26 years: a randomised, double-blind trial

WK Huh, EA Joura, AR Giuliano, OE Iversen… - The Lancet, 2017 - thelancet.com
Background Primary analyses of a study in young women aged 16–26 years showed
efficacy of the nine-valent human papillomavirus (9vHPV; HPV 6, 11, 16, 18, 31, 33, 45, 52 …

Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction

Y Segal, Y Shoenfeld - Cellular & molecular immunology, 2018 - nature.com
Since the early 1800s vaccines have saved numerous lives by preventing lethal infections.
However, during the past two decades, there has been growing awareness of possible …

Prophylactic and therapeutic HPV vaccines: current scenario and perspectives

Y Mo, J Ma, H Zhang, J Shen, J Chen… - Frontiers in cellular …, 2022 - frontiersin.org
Persistent human papillomavirus (HPV) infection is recognized as the main cause of cervical
cancer and other malignant cancers. Although early detection and treatment can be …

A 9-valent HPV vaccine against infection and intraepithelial neoplasia in women

EA Joura, AR Giuliano, OE Iversen… - … England Journal of …, 2015 - Mass Medical Soc
Background The investigational 9-valent viruslike particle vaccine against human
papillomavirus (HPV) includes the HPV types in the quadrivalent HPV (qHPV) vaccine (6 …

[HTML][HTML] Human papillomavirus vaccination: recommendations of the Advisory Committee on Immunization Practices (ACIP)

LE Markowitz, EF Dunne, M Saraiya, HW Chesson… - MMWR Recomm …, 2014 - cdc.gov
This report summarizes the epidemiology of human papillomavirus (HPV) and associated
diseases, describes the licensed HPV vaccines, provides updated data from clinical trials …

Population-level impact and herd effects following human papillomavirus vaccination programmes: a systematic review and meta-analysis

M Drolet, É Bénard, MC Boily, H Ali… - The Lancet infectious …, 2015 - thelancet.com
Background Human papillomavirus (HPV) vaccination programmes were first implemented
in several countries worldwide in 2007. We did a systematic review and meta-analysis to …

Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors

C Simoens, PPL Martin‐Hirsch - Cochrane database of …, 2018 - cochranelibrary.com
Background Persistent infection with high‐risk human papillomaviruses (hrHPV) types is
causally linked with the development of cervical precancer and cancer. HPV types 16 and …