The lens epithelium as a major determinant in the development, maintenance, and regeneration of the crystalline lens
Z Liu, S Huang, Y Zheng, T Zhou, L Hu, L Xiong… - Progress in retinal and …, 2023 - Elsevier
The crystalline lens is a transparent and refractive biconvex structure formed by lens
epithelial cells (LECs) and lens fibers. Lens opacity, also known as cataracts, is the leading …
epithelial cells (LECs) and lens fibers. Lens opacity, also known as cataracts, is the leading …
Vitamin C and the lens: new insights into delaying the onset of cataract
JC Lim, M Caballero Arredondo, AJ Braakhuis… - Nutrients, 2020 - mdpi.com
Cataracts or clouding of the lens is the leading cause of blindness in the world. Age and
diabetes are major risk factors, and with an increasing aging and diabetic population, the …
diabetes are major risk factors, and with an increasing aging and diabetic population, the …
Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research
EA Ainsbury, S Barnard, S Bright, C Dalke… - … Research/Reviews in …, 2016 - Elsevier
The lens of the eye has long been considered as a radiosensitive tissue, but recent research
has suggested that the radiosensitivity is even greater than previously thought. The 2012 …
has suggested that the radiosensitivity is even greater than previously thought. The 2012 …
[HTML][HTML] Aging and age-related diseases of the ocular lens and vitreous body
JM Petrash - Investigative ophthalmology & visual science, 2013 - jov.arvojournals.org
Reduced quality of life and financial burden due to visual impairment and blindness begin to
increase dramatically when individuals reach the age of 40. The major causes of age …
increase dramatically when individuals reach the age of 40. The major causes of age …
Vitrectomy for floaters: prospective efficacy analyses and retrospective safety profile
Purpose: Floaters impact vision but the mechanism is unknown. We hypothesize that floaters
reduce contrast sensitivity function, which can be normalized by vitrectomy, and that …
reduce contrast sensitivity function, which can be normalized by vitrectomy, and that …
Vitreous and vision degrading myodesopsia
J Sebag - Progress in Retinal and Eye Research, 2020 - Elsevier
Macromolecules comprise only 2% of vitreous, yet are responsible for its gel state,
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …
Cataract formation following vitreoretinal procedures
H Feng, RA Adelman - Clinical ophthalmology, 2014 - Taylor & Francis
Purpose To evaluate the incidence and prevalence of cataract formation, progression, and
extraction in patients that underwent vitreoretinal procedures and to evaluate factors that can …
extraction in patients that underwent vitreoretinal procedures and to evaluate factors that can …
Vitreous humor: composition, characteristics and implication on intravitreal drug delivery
Purpose: Intravitreal administration of drug molecules is one of the most common routes for
treating posterior segment eye diseases. However, the properties of vitreous humour …
treating posterior segment eye diseases. However, the properties of vitreous humour …
[HTML][HTML] Molecular processes implicated in human age-related nuclear cataract
RJW Truscott, MG Friedrich - Investigative ophthalmology & …, 2019 - tvst.arvojournals.org
Human age-related nuclear cataract is commonly characterized by four biochemical features
that involve modifications to the structural proteins that constitute the bulk of the lens …
that involve modifications to the structural proteins that constitute the bulk of the lens …
Lens biology and biochemistry
JF Hejtmancik, SA Riazuddin, R McGreal, W Liu… - Progress in molecular …, 2015 - Elsevier
The primary function of the lens resides in its transparency and ability to focus light on the
retina. These require both that the lens cells contain high concentrations of densely packed …
retina. These require both that the lens cells contain high concentrations of densely packed …