Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic
function that provide host defence against microbial infection and tumours. Here, we review …

It is generally accepted that metabolism is able to shape the immune response. Only
recently we are gaining awareness that the metabolic crosstalk between different tumor …

Natural killer (NK) cells play critical roles in host immunity against cancer. In response,
cancers develop mechanisms to escape NK cell attack or induce defective NK cells. Current …

Adoptive transfer of antitumor lymphocytes has gained intense interest in the field of cancer
therapeutics over the past two decades. Human natural killer (NK) cells are a promising …

Natural killer (NK) cells have evolved to complement T and B cells in host defense against
pathogens and cancer. They recognize infected cells and tumors using a sophisticated array …

With the development of technologies that can transform immune cells into therapeutic
modalities, immunotherapy has remarkably changed the current paradigm of cancer …

Natural killer (NK) cells are a promising tool for the use in adoptive immunotherapy, since
they efficiently recognize and kill tumor cells. In this context, ex vivo cultivation is an …

Chimeric antigen receptor T (CAR T) cell therapy achieved remarkable success in B-cell
leukemia and lymphoma which led to its incorporation in treatment protocols for these …

Natural killer (NK) cells recognize deranged cells that display stress receptors or loss of
major histocompatibility complex (MHC) class I. During development, NK cells become …

Cellular therapy has emerged as an attractive option for the treatment of cancer, and
adoptive transfer of chimeric antigen receptor (CAR) expressing T cells has gained FDA …