The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

Breast cancer is the most malignant tumor in women, and there is no absolute cure for it.
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …

This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Enzymes underpin physiological function and exhibit dysregulation in many disease-
associated microenvironments and aberrant cell processes. Exploiting altered enzyme …

The development of stimuli-responsive nanomaterials provides great potential for accurate
diagnosis, effective treatment and precision theranostics. Among the sources of endogenous …

The development of traditional tumor-targeted drug delivery systems based on EPR effect
and receptor-mediated endocytosis is very challenging probably because of the biological …

The successful assembly of large supramolecular structures infers a delicate balance
between reversible noncovalent interactions which are capable of undergoing correction …

The design of internal stimuli-responsive nanocarriers has been extensively used for
delivery of various active compounds including drugs, peptides and genes. These …