Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke
A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
Device-Related Thrombus After Left Atrial Appendage Occlusion: Clinical Impact, Predictors, Classification, and Management
Despite the unprecedented advances in the left atrial appendage occlusion field, device-
related thrombus (DRT) remains an unresolved issue with the therapy. This paper aims to …
related thrombus (DRT) remains an unresolved issue with the therapy. This paper aims to …
Joint analysis of morphological parameters and in silico haemodynamics of the left atrial appendage for thrombogenic risk assessment
MI Pons, J Mill, A Fernandez-Quilez… - Journal of …, 2022 - Wiley Online Library
Background. Atrial fibrillation (AF) is considered the most common human arrhythmia. In
nonvalvular AF, around 99% of thrombi are formed in the left atrial appendage (LAA) …
nonvalvular AF, around 99% of thrombi are formed in the left atrial appendage (LAA) …
[HTML][HTML] Device-related thrombus following left atrial appendage occlusion
Thrombus formation on intracardiac devices remains a subject of importance, with rates in
the 2-5% range. Device-related thrombus (DRT) following left atrial appendage occlusion is …
the 2-5% range. Device-related thrombus (DRT) following left atrial appendage occlusion is …
Impact of occluder device configurations in in-silico left atrial hemodynamics for the analysis of device-related thrombus
C Albors, J Mill, AL Olivares, X Iriart… - PLOS Computational …, 2024 - journals.plos.org
Left atrial appendage occlusion devices (LAAO) are a feasible alternative for non-valvular
atrial fibrillation (AF) patients at high risk of thromboembolic stroke and contraindication to …
atrial fibrillation (AF) patients at high risk of thromboembolic stroke and contraindication to …
A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data
Stroke, a major global health concern often rooted in cardiac dynamics, demands precise
risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2-VASc …
risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2-VASc …
Slow blood-flow in the left atrial appendage is associated with stroke in atrial fibrillation patients
Background Atrial fibrillation (AF) patients are at high risk of stroke with∼ 90% clots
originating from the left atrial appendage (LAA). Clinical understanding of blood-flow based …
originating from the left atrial appendage (LAA). Clinical understanding of blood-flow based …
Impact of left atrial appendage occlusion device position on potential determinants of device-related thrombus: a patient-specific in silico study
Z Zhong, Y Gao, S Kovács, V Vij, D Nelles… - Clinical Research in …, 2024 - Springer
Background Device-related thrombus (DRT) after left atrial appendage occlusion (LAAO) is
potentially linked to adverse events. Although clinical reports suggest an effect of the device …
potentially linked to adverse events. Although clinical reports suggest an effect of the device …
Preliminary findings on left atrial appendage occlusion simulations applying different endocardial devices
N D'Alessandro, M Falanga, A Masci… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) is one of the most investigated arrhythmias since it is associated with a
five-fold increase in the risk of strokes. Left atrium dilation and unbalanced and irregular …
five-fold increase in the risk of strokes. Left atrium dilation and unbalanced and irregular …
A digital twin approach for stroke risk assessment in Atrial Fibrillation Patients
M Falanga, C Cortesi, A Chiaravalloti, A Dal Monte… - Heliyon, 2024 - cell.com
Atrial fibrillation (AF) is associated with a fivefold increased risk of cerebrovascular events,
contributing to 15–18% of all strokes. Stroke prevention in clinical practice is typically guided …
contributing to 15–18% of all strokes. Stroke prevention in clinical practice is typically guided …