Advances in oral drug delivery for regional targeting in the gastrointestinal tract-influence of physiological, pathophysiological and pharmaceutical factors
S Hua - Frontiers in pharmacology, 2020 - frontiersin.org
The oral route is by far the most common route of drug administration in the gastrointestinal
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …
[HTML][HTML] Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium
The transcytosis of antigens across the gut epithelium by microfold cells (M cells) is
important for the induction of efficient immune responses to some mucosal antigens in …
important for the induction of efficient immune responses to some mucosal antigens in …
Prospects for mucosal vaccine: shutting the door on SARS-CoV-2
The sudden emergence of a highly transmissible and pathogenic coronavirus SARS-CoV-2
in December 2019 from China and its rapid global spread has posed an international health …
in December 2019 from China and its rapid global spread has posed an international health …
Nanomedicine in the management of microbial infection–overview and perspectives
For more than 2 billion years, microbes have reigned on our planet, evolving or outlasting
many obstacles they have encountered. In the 20th century, this trend took a dramatic turn …
many obstacles they have encountered. In the 20th century, this trend took a dramatic turn …
Overcoming the intestinal barrier: a look into targeting approaches for improved oral drug delivery systems
Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …
Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses
MO Oyewumi, A Kumar, Z Cui - Expert review of vaccines, 2010 - Taylor & Francis
The development of novel immune adjuvants is emerging as a significant area of vaccine
delivery based on the continued necessity to amplify immune responses to a wide array of …
delivery based on the continued necessity to amplify immune responses to a wide array of …
Outer membrane vesicles: current status and future direction of these novel vaccine adjuvants
K Tan, R Li, X Huang, Q Liu - Frontiers in microbiology, 2018 - frontiersin.org
Adjuvants have been of great interest to vaccine formulation as immune-stimulators. Prior to
the recent research in the field of immune stimulation, conventional adjuvants utilized for …
the recent research in the field of immune stimulation, conventional adjuvants utilized for …
Novel adjuvants & delivery vehicles for vaccines development: a road ahead
The pure recombinant and synthetic antigens used in modern day vaccines are generally
less immunogenic than older style live/attenuated and killed whole organism vaccines. One …
less immunogenic than older style live/attenuated and killed whole organism vaccines. One …
Nanocarriers transport across the gastrointestinal barriers: the contribution to oral bioavailability via blood circulation and lymphatic pathway
D Wang, Q Jiang, Z Dong, T Meng, F Hu, J Wang… - Advanced Drug Delivery …, 2023 - Elsevier
Oral administration is the preferred route of drug delivery in clinical practice due to its
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …
Oral and intranasal vaccines against SARS‐CoV‐2: Current progress, prospects, advantages, and challenges
Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
caused a deadly pandemic in the 21st century, resulting in many deaths, economic loss, and …
caused a deadly pandemic in the 21st century, resulting in many deaths, economic loss, and …