Diversity, evolutionary contribution and ecological roles of aquatic viruses

QY Zhang, JF Gui - Science China Life Sciences, 2018 - Springer
Aquatic viruses include infected viruses in aquatic animals, plants and microorganisms, and
free-floating viruses (virioplankton) in water environments. In the last three decades, a huge …

Extraordinary diversity of viruses in deep‐sea sediments as revealed by metagenomics without prior virion separation

X Zheng, W Liu, X Dai, Y Zhu, J Wang… - Environmental …, 2021 - Wiley Online Library
Our current knowledge of the virosphere in deep‐sea sediments remains rudimentary. Here
we investigated viral diversity at both gene and genomic levels in deep‐sea sediments of …

Discovery of the deep-sea NEOM Brine Pools in the Gulf of Aqaba, Red Sea

SJ Purkis, H Shernisky, PK Swart, A Sharifi… - … Earth & Environment, 2022 - nature.com
Deep-sea brine pools represent hypersaline environments famed for their extremophile
microbes. With anoxia entirely excluding bioturbating megafauna, brine pools are also …

Novel thermostable antibiotic resistance enzymes from the Atlantis II Deep Red Sea brine pool

AHA Elbehery, DJ Leak, R Siam - Microbial Biotechnology, 2017 - Wiley Online Library
The advent of metagenomics has greatly facilitated the discovery of enzymes with useful
biochemical characteristics for industrial and biomedical applications, from environmental …

Insights into red sea brine pool specialized metabolism gene clusters encoding potential metabolites for biotechnological applications and extremophile survival

L Ziko, M Adel, MN Malash, R Siam - Marine drugs, 2019 - mdpi.com
The recent rise in antibiotic and chemotherapeutic resistance necessitates the search for
novel drugs. Potential therapeutics can be produced by specialized metabolism gene …

A novel thermostable and halophilic thioredoxin reductase from the Red Sea Atlantis II hot brine pool

EA Badiea, AA Sayed, M Maged, WM Fouad… - PLoS …, 2019 - journals.plos.org
The highly extreme conditions of the lower convective layer in the Atlantis II (ATII) Deep
brine pool of the Red Sea make it an ideal environment for the search for novel enzymes …

Active prokaryotic and eukaryotic viral ecology across spatial scale in a deep-sea brine pool

B Minch, M Chakraborty, S Purkis… - ISME …, 2024 - academic.oup.com
Deep-sea brine pools represent rare, extreme environments, providing unique insight into
the limits of life on Earth, and by analogy, the plausibility of life beyond it. A distinguishing …

Characterization of a novel peptide mined from the Red Sea brine pools and modified to enhance its anticancer activity

YT Abdou, SM Saleeb, KMA Abdel-Raouf, M Allam… - BMC cancer, 2023 - Springer
Drug resistance is a major cause of the inefficacy of conventional cancer therapies, and
often accompanied by severe side effects. Thus, there is an urgent need to develop novel …

The association of group IIB intron with integrons in hypersaline environments

S Sonbol, R Siam - Mobile DNA, 2021 - Springer
Background Group II introns are mobile genetic elements used as efficient gene targeting
tools. They function as both ribozymes and retroelements. Group IIC introns are the only …

Molecular and functional characterization of unique thermo-halophilic thioredoxin from the metagenome of an exotic environment

MG AbdelWahed, EA Badiea, A Ouf… - International journal of …, 2020 - Elsevier
The lower convective layer (LCL) at Atlantis II brine pool of the Red sea represents one of
the exceptional, unique ecosystems. Thioredoxin is a multi-functional antioxidant redox …