Immunobiology of Crimean-Congo hemorrhagic fever

SE Rodriguez, DW Hawman, TE Sorvillo, TJ O'Neal… - Antiviral research, 2022 - Elsevier
Abstract Human infection with Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-
borne pathogen in the family Nairoviridae, can result in a spectrum of outcomes, ranging …

Animal models for Crimean-Congo hemorrhagic fever human disease

AR Garrison, DR Smith, JW Golden - Viruses, 2019 - mdpi.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is an important tick-borne human
pathogen endemic throughout Asia, Africa and Europe. CCHFV is also an emerging virus …

The host inflammatory response contributes to disease severity in Crimean-Congo hemorrhagic fever virus infected mice

JW Golden, X Zeng, CR Cline, JM Smith… - PLoS …, 2022 - journals.plos.org
Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen. In cell
culture, CCHFV is sensed by the cytoplasmic RNA sensor retinoic acid-inducible gene I (RIG …

In silico formulation of a next-generation multiepitope vaccine for use as a prophylactic candidate against Crimean-Congo hemorrhagic fever

R Alam, A Samad, F Ahammad, SM Nur, AA Alsaiari… - BMC medicine, 2023 - Springer
Abstract Background Crimean-Congo hemorrhagic fever (CCHF) is a widespread disease
transmitted to humans and livestock animals through the bite of infected ticks or close …

Exploring Crimean-Congo hemorrhagic fever virus-induced hepatic injury using antibody-mediated type I interferon blockade in mice

ME Lindquist, X Zeng, LA Altamura, SP Daye… - Journal of …, 2018 - Am Soc Microbiol
Crimean-Congo hemorrhagic fever virus (CCHFV) can cause severe hepatic injury in
humans. However, the mechanism (s) causing this damage is poorly characterized. CCHFV …

Crimean–Congo hemorrhagic fever virus: progress in vaccine development

A Ozdarendeli - Diagnostics, 2023 - mdpi.com
Crimean–Congo hemorrhagic fever virus (CCHFV), a member of the Nairoviridae family and
Bunyavirales order, is transmitted to humans via tick bites or contact with the blood of …

[PDF][PDF] Scoping review of Crimean-Congo hemorrhagic fever (CCHF) literature and implications of future research

B Wahid, S Altaf, N Naeem, N Ilyas… - J Coll Physicians Surg …, 2019 - academia.edu
Crimean-Congo hemorrhagic fever (CCHF) is one of the severe forms of high-fatality
hemorrhagic fever transmitted by bite of infected ticks or body fluids of infected individuals …

Effect of TLR10 (2322A/G, 720A/C, and 992T/A) polymorphisms on the pathogenesis of Crimean Congo hemorrhagic fever disease

S Kızıldağ, S Arslan, N Özbilüm… - Journal of Medical …, 2018 - Wiley Online Library
Crimean Congo hemorrhagic fever (CCHF) is a tick‐borne disease caused by the Crimean
Congo hemorrhagic fever virus (CCHFV). Toll‐like receptors (TLRs) are type 1 …

Sequence optimized real-time reverse transcription polymerase chain reaction assay for detection of Crimean-Congo hemorrhagic fever virus

JW Koehler, KL Delp, AT Hall… - … American journal of …, 2017 - pmc.ncbi.nlm.nih.gov
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus of the genus
Nairovirus within the family Bunyaviridae. Infection can result in general myalgia, fever, and …

Methylene-tetrahydrofolate reductase gene C677T and A1298C polymorphisms as a risk factor for Crimean-Congo hemorrhagic fever

N Karakus, F Duygu, A Rustemoglu… - … , Nucleotides & Nucleic …, 2022 - Taylor & Francis
Crimean-Congo hemorrhagic fever (CCHF) is a deadly viral disease. Methylene-
tetrahydrofolate reductase (MTHFR) has an important role in folate metabolism, and also in …