The AAA+ superfamily: a review of the structural and mechanistic principles of these molecular machines
ATPases associated with diverse cellular activities (AAA+ proteins) are a superfamily of
proteins found throughout all domains of life. The hallmark of this family is a conserved …
proteins found throughout all domains of life. The hallmark of this family is a conserved …
The molecular principles governing the activity and functional diversity of AAA+ proteins
ATPases associated with diverse cellular activities (AAA+ proteins) are macromolecular
machines that convert the chemical energy contained in ATP molecules into powerful …
machines that convert the chemical energy contained in ATP molecules into powerful …
PEX5 translocation into and out of peroxisomes drives matrix protein import
ML Skowyra, TA Rapoport - Molecular cell, 2022 - cell.com
Peroxisomes are ubiquitous organelles whose dysfunction causes fatal human diseases.
Most peroxisomal enzymes are imported from the cytosol by the receptor PEX5, which …
Most peroxisomal enzymes are imported from the cytosol by the receptor PEX5, which …
Protein import into peroxisomes occurs through a nuclear pore–like phase
Peroxisomes are ubiquitous organelles whose dysfunction causes fatal human diseases.
Most peroxisomal proteins are imported from the cytosol in a folded state by the soluble …
Most peroxisomal proteins are imported from the cytosol in a folded state by the soluble …
A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel
Peroxisomes are ubiquitous organelles that house various metabolic reactions and are
essential for human health,,–. Luminal peroxisomal proteins are imported from the cytosol by …
essential for human health,,–. Luminal peroxisomal proteins are imported from the cytosol by …
Protocols for molecular modeling with Rosetta3 and RosettaScripts
Previously, we published an article providing an overview of the Rosetta suite of
biomacromolecular modeling software and a series of step-by-step tutorials [Kaufmann, KW …
biomacromolecular modeling software and a series of step-by-step tutorials [Kaufmann, KW …
The peroxisome: an update on mysteries 2.0
M Islinger, A Voelkl, HD Fahimi, M Schrader - Histochemistry and cell …, 2018 - Springer
Peroxisomes are key metabolic organelles, which contribute to cellular lipid metabolism, eg
the β-oxidation of fatty acids and the synthesis of myelin sheath lipids, as well as cellular …
the β-oxidation of fatty acids and the synthesis of myelin sheath lipids, as well as cellular …
Peroxisome function, biogenesis, and dynamics in plants
Peroxisome Function, Biogenesis, and Dynamics in Plants | Plant Physiology | Oxford
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Comparative genomics of peroxisome biogenesis proteins: making sense of the PEX proteins
RLM Jansen, C Santana-Molina… - Frontiers in cell and …, 2021 - frontiersin.org
PEX genes encode proteins involved in peroxisome biogenesis and proliferation. Using a
comparative genomics approach, we clarify the evolutionary relationships between the 37 …
comparative genomics approach, we clarify the evolutionary relationships between the 37 …
Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1–Npl4
Many polyubiquitinated proteins are extracted from membranes or complexes by the
conserved ATPase Cdc48 (in yeast; p97 or VCP in mammals) before proteasomal …
conserved ATPase Cdc48 (in yeast; p97 or VCP in mammals) before proteasomal …