Mismatch repair pathway, genome stability and cancer

N Pećina-Šlaus, A Kafka, I Salamon… - Frontiers in molecular …, 2020 - frontiersin.org
The acquisition of genomic instability is one of the key characteristics of the cancer cell, and
microsatellite instability (MSI) is an important segment of this phenomenon. This review aims …

Neurofibromatosis type 2 (NF2) and the implications for vestibular schwannoma and meningioma pathogenesis

S Bachir, S Shah, S Shapiro, A Koehler… - International journal of …, 2021 - mdpi.com
Patients diagnosed with neurofibromatosis type 2 (NF2) are extremely likely to develop
meningiomas, in addition to vestibular schwannomas. Meningiomas are a common primary …

Deep sequencing reveals recurrent somatic mutations and distinct molecular subgroups in gastric cancer in Mizo population, North East India

P Chakraborty, S Kurkalang, S Ghatak, S Das… - Genomics, 2023 - Elsevier
Abstract In India, Mizoram has the highest incidence of gastric cancer (GC) which might be
associated with environmental factors such as diet, Helicobacter pylori (H. pylori) and …

Are we benign? What can Wnt signaling pathway and epithelial to mesenchymal transition tell us about intracranial meningioma progression

A Bukovac, A Kafka, M Raguž, P Brlek, K Dragičević… - Cancers, 2021 - mdpi.com
Simple Summary Intracranial meningiomas are one of the most common primary brain
tumors. Although mostly benign, a small portion may exhibit aggressive and malignant …

Immunohistochemical expression pattern of mismatch repair genes in the short-term streptozotocin-induced diabetic rat kidneys

M Dragun, N Filipović, A Racetin, S Kostić… - Applied …, 2021 - journals.lww.com
We studied the expression of mismatch repair genes (MMRs)—mutS protein homolog 2
(MSH2), PMS2, MutL homolog 1 (MLH1), and yH2AFX in diabetic rat kidneys. Streptozotocin …

Genomic sequencing of a pregnancy associated symptomatic meningioma of the diaphragma sellae: a case report

NK Leclair, WA Lambert, Q Wu… - British Journal of …, 2024 - Taylor & Francis
Pregnancy-associated meningiomas have unique considerations and features regarding
their pathophysiology, location, genetic profile, and neurosurgical management. These …

Promjene gena DVL1 u intrakranijalnim meningeomima čovjeka

K Dragičević - 2021 - repozitorij.pmf.unizg.hr
Sažetak Meningeomi su najčešći primarni tumori središnjeg živčanog sustava, koji u manje
od 20% slučajeva mogu pokazivati agresivnost, recidive i metastaze. Među signalnim …

Utjecaj izmjene Ei N-kadherina na fosforilacijski status beta-katenina i epitelno-mezenhimsku tranziciju u intrakranijalnim meningeomima

A Bukovac - 2020 - dr.nsk.hr
Sažetak Epitelno-mezenhimska tranzicija (EMT) koju karakterizira kadherinska izmjena,
odnosno smanjena ekspresija E-kadherina, a pojačana N-kadherina, ima važnu ulogu u …

THE ROLE OF POSTREPLICATIVE MISMATCHREPAIR (MMR) IN TUMORIGENESIS.

N Pećina-Šlaus, A Kafka… - Rad Hrvatske Akademije …, 2018 - search.ebscohost.com
Impaired cellular DNA mismatchrepair (MMR) mechanisms are involved in cancer initiation
and progression. Cancer cells are thought to have a mutator phenotype in which an …

Cancer Prohibitor-Telomeric DNA Repair Pathways

PP Jia, HP Shi - Journal of Nutritional Oncology, 2018 - journals.lww.com
Telomeres are DNA-protein structures that form protective caps at the end of eukaryotic
chromosomes, safeguarding the chromosomes from degradation and maintaining the …