Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

[HTML][HTML] Targeting hydrogen sulphide signaling in breast cancer

RA Youness, AZ Gad, K Sanber, YJ Ahn, GJ Lee… - Journal of advanced …, 2021 - Elsevier
Abstract Introduction Hydrogen sulphide (H 2 S) has been established as a key member of
the gasotransmitters family that recently showed a pivotal role in various pathological …

Role of miR-155 in inflammatory autoimmune diseases: a comprehensive review

WD Xu, SY Feng, AF Huang - Inflammation Research, 2022 - Springer
Purpose MiR-155 is a member of the microRNAs (miRNAs) family and regulates gene
expression post-transcriptionally by binding to the 3'UTR of target mRNA. MiR-155 has a …

LncRNA HEIH/miR‐939‐5p interplay modulates triple‐negative breast cancer progression through NOS2‐induced nitric oxide production

H Nafea, RA Youness, K Abou‐Aisha… - Journal of Cellular …, 2021 - Wiley Online Library
This study aimed to unravel the regulatory role of noncoding RNAs (ncRNA) on the nitric
oxide (NO) machinery system in triple‐negative breast cancer (TNBC) patients and to further …

Immunological involvement of microRNAs in the key events of systemic lupus erythematosus

M Chi, K Ma, Y Li, M Quan, Z Han, Z Ding… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is an archetype autoimmune disease characterized by
a myriad of immunoregulatory abnormalities that drives injury to multiple tissues and organs …

Circulating exosomal microRNAs as biomarkers of systemic lupus erythematosus

W Li, S Liu, Y Chen, R Weng, K Zhang, X He, C He - Clinics, 2020 - SciELO Brasil
OBJECTIVES: Many studies indicate that microRNAs (miRNAs) could be potential
biomarkers for various diseases. The purpose of this study was to investigate the clinical …

The involvement of microRNAs in modulation of innate and adaptive immunity in systemic lupus erythematosus and lupus nephritis

M Honarpisheh, P Köhler… - Journal of …, 2018 - Wiley Online Library
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), represent a family of RNA
molecules that do not translate into protein. Nevertheless, they have the ability to regulate …

Hindering the synchronization between miR-486-5p and H19 lncRNA by hesperetin halts breast cancer aggressiveness through tuning ICAM-1

RM Abdallah, AM Elkhouly, RA Soliman… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: Recently, a novel crosstalk between non-coding RNAs (ncRNAs) has been
casted. However, this has been seldom investigated in metastatic BC (mBC). H19 and miR …

Identification and contribution of inflammation-induced novel MicroRNA in the pathogenesis of systemic lupus erythematosus

RP Singh, BH Hahn, DS Bischoff - Frontiers in Immunology, 2022 - frontiersin.org
Recently microRNAs (miRNAs) have been recognized as powerful regulators of many
genes and pathways involved in the pathogenesis of inflammatory diseases including …

Long Non-Coding RNA LINC00324 Exerts Pro-Tumorigenic Effects on Liver Cancer Stem Cells by Up-Regulating Fas Ligand via PU Box Binding Protein

J Gao, C Dai, X Yu, XB Yin, F Zhou - 2019 - papers.ssrn.com
Background: Hepatocellular carcinoma (HCC) represents a major cause of cancer death,
but the molecular mechanism for its development has not been well characterized yet. Long …