Microbiome engineering for sustainable agriculture: using synthetic biology to enhance nitrogen metabolism in plant-associated microbes
SW Han, Y Yoshikuni - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Plant–microbe interactions are central to sustainable agriculture.•Nitrogen
metabolites play essential roles in plant-growth promotion.•Pyridoxal-5′-phosphate …
metabolites play essential roles in plant-growth promotion.•Pyridoxal-5′-phosphate …
The tricarboxylic acid cycle as a central regulator of the rate of aging: implications for metabolic interventions
JM Borkum - Advanced Biology, 2023 - Wiley Online Library
Certain metabolic interventions such as caloric restriction, fasting, exercise, and a ketogenic
diet extend lifespan and/or health span. However, their benefits are limited and their …
diet extend lifespan and/or health span. However, their benefits are limited and their …
PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma
X Hu, Y He, Z Han, W Liu, D Liu, X Zhang, L Chen… - Cell death & …, 2022 - nature.com
Effective strategies for hepatocellular carcinoma, which is the second leading cause of death
worldwide, remain limited. A growing body of emerging evidence suggests that ferroptosis …
worldwide, remain limited. A growing body of emerging evidence suggests that ferroptosis …
Microbial metabolic flexibility guarantees function resilience in response to starvation disturbance
YC Wang, YH Lv, XR Hu, YT Lin, JC Crittenden… - Bioresource …, 2024 - Elsevier
Starvation disturbance due to nutrient limitation is a common problem in bioreactors.
However, an understanding of how microbial systems respond to starvation remains in its …
However, an understanding of how microbial systems respond to starvation remains in its …
Proteaphagy is specifically regulated and requires factors dispensable for general autophagy
KA Waite, A Burris, G Vontz, A Lang… - Journal of Biological …, 2022 - ASBMB
Changing physiological conditions can increase the need for protein degradative capacity in
eukaryotic cells. Both the ubiquitin-proteasome system and autophagy contribute to protein …
eukaryotic cells. Both the ubiquitin-proteasome system and autophagy contribute to protein …
[HTML][HTML] Ethanol-lactate transition of Lachancea thermotolerans is linked to nitrogen metabolism
Climate change increases sugar content in grapes, resulting in unwanted increase in
ethanol content of wine. Lachancea thermotolerans ferments glucose and fructose into both …
ethanol content of wine. Lachancea thermotolerans ferments glucose and fructose into both …
[HTML][HTML] Autophagy–urea cycle pathway is essential for the statin-mediated nitric oxide bioavailability in endothelial cells
WH Chen, BC Guo, CH Chen, MC Hsu… - Journal of Food and …, 2023 - ncbi.nlm.nih.gov
Statins induce nitric oxide (NO) bioavailability by activating endothelial nitric oxide synthase
via kinase-and calcium-dependent pathways in endothelial cells (ECs). However, their effect …
via kinase-and calcium-dependent pathways in endothelial cells (ECs). However, their effect …
The Change in Whole-Genome Methylation and Transcriptome Profile under Autophagy Defect and Nitrogen Starvation
Y Shi, B Yu, S Cheng, W Hu, F Liu - International Journal of Molecular …, 2023 - mdpi.com
Through whole-genome bisulfite sequencing and RNA-seq, we determined the potential
impact of autophagy in regulating DNA methylation in Arabidopsis, providing a solid …
impact of autophagy in regulating DNA methylation in Arabidopsis, providing a solid …
Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy
Macroautophagy (hereafter, autophagy) is a process that directs the degradation of
cytoplasmic material in lysosomes. In addition to its homeostatic roles, autophagy …
cytoplasmic material in lysosomes. In addition to its homeostatic roles, autophagy …
Antibacterial activity and mechanism of a novel bacteriocin produced by Lactiplantibacillus plantarum against Escherichia coli and Staphylococcus aureus
Z Xu, J Wang, W Zheng, S Zhao… - … Journal of Food …, 2023 - Wiley Online Library
The purpose of the study was to explore the antibacterial effect and mechanism of a novel
bacteriocin of Lactiplantibacillus plantarum (L. plantarum) against Escherichia coli (E. coli) …
bacteriocin of Lactiplantibacillus plantarum (L. plantarum) against Escherichia coli (E. coli) …