Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor involved in
homeostatic regulation of normal cells and carcinogenesis of epithelial malignancies. With …

Oral cancer, as one of the most prevalent and invasive cancers that invade local tissue, can
cause metastasis, and have high mortality. In 2018, around 355,000 worldwide oral cancers …

Tumor‐targeting monoclonal antibodies are available for a number of cancer cell types
(over) expressing the corresponding tumor antigens. Such antibodies can limit tumor …

Cancer and autoimmune disease are closely related, and many therapeutic antibodies are
widely used in clinics for the treatment of both diseases. Among them, the anti-CD20 …

Therapeutic monoclonal antibodies (mAb), directed toward either tumor antigens or
inhibitory checkpoints on immune cells, are effective in cancer therapy. Increasing evidence …

Simple Summary Immunotherapy aims to engage various immune cells in the elimination of
cancer cells. Neutrophils are the most abundant leukocytes in the circulation and have …

Malaria transmission-blocking vaccines candidates based on Pfs25 and Pfs230 have
advanced to clinical studies. Exoprotein A (EPA) conjugate of Pfs25 in Alhydrogel® …

The tumor immune microenvironment plays a vital role in the metastasis of colorectal cancer.
As one of the most important immune cells, macrophages act as phagocytes, patrol the …

Anti-CD20 antibodies such as rituximab are broadly used to treat B-cell malignancies. These
antibodies can induce various effector functions, including immune cell-mediated antibody …

Background In 2014, we first described novel autoantibodies to the inositol 1, 4, 5-
trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar …