Catestatin is a multifunctional peptide that is involved in the regulation of the cardiovascular
and immune systems as well as metabolic homeostatis. It mitigates detrimental, excessive …

Chromogranin A (CgA)—the index member of the chromogranin/secretogranin secretory
protein family—is ubiquitously distributed in endocrine, neuroendocrine, and immune cells …

Background: Cardiovascular disease (CVD), the most common cause of death globally,
accounts for~ 30% of all deaths worldwide. Hypertension is a common contributor to …

Obesity, lipodystrophy, diabetes, and hypertension collectively constitute the main features
of Metabolic Syndrome (MetS), together with insulin resistance (IR), which is considered as …

Dense core vesicles (DCVs) and synaptic vesicles are specialised secretory vesicles in
neurons and neuroendocrine cells, and abnormal release of their cargo is associated with …

The rapid increase in drug-resistant and multidrug-resistant infections poses a serious
challenge to antimicrobial therapies, and has created a global health crisis. Since …

Human chromogranin A (CgA), a 439 residue-long member of the “granin” secretory protein
family, is the precursor of several peptides and polypeptides involved in the regulation of the …

Catestatin (CST), an endogenous antihypertensive/antiadrenergic peptide, is a novel
regulator of cardiovascular physiology. Here, we report case–control studies in 2 …

Chromogranin A (CHGA), a member of the granin family of proteins, has been an attractive
therapeutic target and candidate biomarker for several cardiovascular, neurological, and …

Catestatin (CST), a chromogranin A (CHGA)-derived peptide, is a potent inhibitor of
catecholamine release from adrenal chromaffin cells and postganglionic sympathetic axons …