Extensively drug‐resistant (XDR) typhoid: evolution, prevention, and its management

J Akram, AS Khan, HA Khan, SA Gilani… - BioMed Research …, 2020 - Wiley Online Library
Typhoid fever is the result of a human host‐restricted Salmonella enteric serotype typhi
infection that causes enteric fever. Around 21 million people contract typhoid annually, with …

Progress on the national action plan of Pakistan on antimicrobial resistance (AMR): A narrative review and the implications

Z Saleem, B Godman, F Azhar… - Expert review of anti …, 2022 - Taylor & Francis
Introduction The emergence of antimicrobial resistance (AMR) is a threat to public health. In
2015, the World Health Organization (WHO) introduced a global action plan to tackle AMR in …

Vi-specific serological correlates of protection for typhoid fever

C Jin, J Hill, BM Gunn, WH Yu, LC Dahora… - Journal of Experimental …, 2020 - rupress.org
Typhoid Vi vaccines have been shown to be efficacious in children living in endemic
regions; however, a widely accepted correlate of protection remains to be established. We …

[HTML][HTML] Morbidity and mortality associated with typhoid fever among hospitalized patients in Hyderabad district, Pakistan, 2017-2018: retrospective record review

M Fatima, S Kumar, M Hussain… - JMIR Public Health …, 2021 - publichealth.jmir.org
Background Hyderabad, Pakistan, was the first city to witness an outbreak of extensively
drug resistant (XDR) typhoid fever. The outbreak strain is resistant to ampicillin …

Longer-term assessment of azithromycin for reducing childhood mortality in Africa

JD Keenan, AM Arzika, R Maliki… - … England Journal of …, 2019 - Mass Medical Soc
Abstract Background The MORDOR I trial (Macrolides Oraux pour Réduire les Décès avec
un Oeil sur la Résistance) showed that in Niger, mass administration of azithromycin twice a …

Antibiotic consumption among hospitalized neonates and children in Punjab province, Pakistan

ZU Mustafa, M Salman, M Yasir, B Godman… - Expert review of anti …, 2022 - Taylor & Francis
Background Periodic surveillance of antibiotic consumption in the form of point prevalence
studies is a quick and robust methodology to evaluate prescribing trends in hospitals. The …

[HTML][HTML] A skeleton in the closet: the implications of COVID-19 on XDR strain of typhoid in Pakistan

S Ahmad, C Tsagkaris, AT Aborode, MTU Haque… - Public health in …, 2021 - Elsevier
Extensively drug resistant typhoid fever is a major public health concern in Pakistan. During
the COVID-19 pandemic, poor sanitation is leading typhoid cases to a surge and obsolete …

[HTML][HTML] Antimicrobial resistant strains of Salmonella typhi: The role of illicit antibiotics sales, misuse, and self-medication practices in Pakistan

OA Shaikh, Z Asghar, RM Aftab, S Amin… - Journal of Infection and …, 2023 - Elsevier
Typhoid fever, caused by the bacterium Salmonella typhi, is an often-fatal illness prevalent
in Africa and South Asia. The illness has seen an alarming rise in multi-drug-resistant (MDR) …

Emerging Trends of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Salmonella Typhi in a Tertiary Care Hospital of Lahore, Pakistan

M Zakir, M Khan, MI Umar, G Murtaza, M Ashraf… - Microorganisms, 2021 - mdpi.com
Salmonella Typhi is a Gram-negative pathogen that causes typhoid fever in humans. The
use of antibiotics to treat typhoid has considerably mitigated its fatality risk, but rising …

New immunization strategies: adapting to global challenges

C Mantel, T Cherian - Bundesgesundheitsblatt-Gesundheitsforschung …, 2020 - Springer
Immunization has made an enormous contribution to global health. Global vaccination
coverage has dramatically improved and mortality rates among children due to vaccine …