Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

The discovery of several revitalizing molecules that can stop or reduce the pathology of a
wide range of diseases will be considered a major breakthrough of the present time …

Aberrant DNA methylation is an epigenetic hallmark of melanoma, known to play important
roles in melanoma formation and progression. Recent advances in genome-wide …

Cancer is one of the most complex and systemic diseases affecting the health of mankind,
causing major deaths with a significant increase. This pathology is caused by several risk …

The human disease methylation database (DiseaseMeth, http://bioinfo. hrbmu. edu.
cn/diseasemeth/) is an interactive database that aims to present the most complete …

Gene mutations are strongly associated with tumor progression and are well known in
cancer development. However, recently discovered epigenetic alterations have shown the …

A plethora of studies have shown that both DNMT1 and EZH2 have great effects on the
progression of a variety of cancers. However, it remains unclear whether the expression …

Abstract The Cancer Genome Atlas (TCGA) has accrued RNA-Seq-based transcriptome
data for more than 4000 cancer tissue samples across 12 cancer types, translating these …

Protein methyltransferases have been shown to methylate histone and non-histone proteins,
leading to regulation of several biological processes that control cell homeostasis. Over the …

Long-term exposure to fine particulate matter (PM2. 5) has been reported to be closely
associated with the increased lung cancer risk in populations, but the mechanisms …