Placental transporter localization and expression in the human: the importance of species, sex, and gestational age differences

N Walker, P Filis, U Soffientini… - Biology of …, 2017 - academic.oup.com
The placenta is a critical organ during pregnancy, essential for the provision of an optimal
intrauterine environment, with fetal survival, growth, and development relying on correct …

Androgens in maternal vascular and placental function: implications for preeclampsia pathogenesis

S Kumar, GH Gordon, DH Abbott, JS Mishra - Reproduction, 2018 - rep.bioscientifica.com
Adequate maternal vascular adaptations and blood supply to the uterus and placenta are
crucial for optimal oxygen and nutrient transport to growing fetuses of eutherian mammals …

Androgen receptor in the ovary theca cells plays a critical role in androgen-induced reproductive dysfunction

Y Ma, S Andrisse, Y Chen, S Childress, P Xue… - …, 2017 - academic.oup.com
Androgen and its receptor (AR) play a critical role in reproductive function under both
physiological and pathophysiological conditions. Female AR global knockout mice are …

A narrative review of placental contribution to adverse pregnancy outcomes in women with polycystic ovary syndrome

AS Kelley, YR Smith… - The Journal of Clinical …, 2019 - academic.oup.com
Context Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of
reproductive-aged women. In pregnancy, women with PCOS experience increased risk of …

Elevated gestational testosterone impacts vascular and uteroplacental function

S Kumar, R Song, JS Mishra - Placenta, 2024 - Elsevier
Maternal vascular adaptations to establish an adequate blood supply to the uterus and
placenta are essential for optimal nutrient and oxygen delivery to the developing fetus in …

Electroacupuncture alleviates surgical trauma-induced hypothalamus pituitary adrenal axis hyperactivity via microRNA-142

J Zhu, Z Chen, Z Meng, M Ju, M Zhang… - Frontiers in Molecular …, 2017 - frontiersin.org
Electroacupuncture (EA) could improve the hyperactivity of the hypothalamus pituitary
adrenal (HPA) axis induced by hepatectomy. However, its underlying mechanism still …

Mice exposed to maternal androgen excess and diet-induced obesity have altered phosphorylation of catechol-O-methyltransferase in the placenta and fetal liver

R Fornes, M Manti, X Qi, E Vorontsov… - International Journal of …, 2019 - nature.com
Background/objectives Maternal obesity together with androgen excess in mice negatively
affects placental function and maternal and fetal liver function as demonstrated by increased …

The balance between cell survival and death in the placenta: Do neurotrophins have a role?

P Pathare-Ingawale… - Systems Biology in …, 2022 - Taylor & Francis
Neurotrophins (NT) are a closely related family of growth factors, which regulate the nervous
system's development, maintenance, and function. Although NTs have been well studied in …

Nerve growth factor levels in term human infants: relationship to prenatal growth and early postnatal feeding

D Sánchez-Infantes, R Cereijo… - International Journal …, 2018 - Wiley Online Library
Background. Nerve growth factor (NGF) plays a key role in neuroprotection and
developmental maturity. We assessed longitudinally the circulating concentrations of NGF in …

Per-and polyfluoroalkyl substances (PFAS) and hypertensive disorders of Pregnancy-integration of epidemiological and mechanistic evidence

SV Dangudubiyyam, A Hofmann, P Yadav… - Reproductive …, 2024 - Elsevier
Background Hypertensive disorders of pregnancy (HDP) remain a significant global health
burden despite medical advancements. HDP prevalence appears to be rising, leading to …