Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …

Abstract Development of carrier-based dry powder inhalation formulations follows till date
empirical approaches. This is mainly underlain by numerousness of interplaying …

The aim of the study was to investigate how the fine particle content of lactose carriers
prepared with different types of lactose fines regulates dry powder inhaler (DPI) formulation …

Understanding and controlling powder de-agglomeration is of great importance in the
development of dry powder inhaler (DPI) products. Dry dispersion laser diffraction measures …

A concept of mixing energy, ME, has been developed and applied to blending of adhesive
mixtures for inhalation in a high shear blender. Six different systems were investigated, four …

The synthonic modeling approach provides a molecule-centered understanding of the
surface properties of crystals. It has been applied extensively to understand crystallization …

Abstract Rosuvastatin (RSVS), an anti-lipidemic agent suggested for the treatment of airway
remodeling in chronic obstructive pulmonary disease (COPD). It shows a pleiotropic effect …

Purpose The objective of this study was to explore the performance of a high efficiency dry
powder inhaler (DPI) intended for excipient enhanced growth (EEG) aerosol delivery based …

The aim of this study was to evaluate the influence of novel engineered fine mannitol
particles (4.7%, w/w) on the performance of lactose–salbutamol sulphate dry powder inhaler …

The work presented in this paper employed a resonant acoustic mixing (RAM) process to
optimize the fine particle agglomeration process for dry powder inhalation to achieve …