Sonic hedgehog (Shh) signaling plays a critical role in regulating cerebellum development
by maintaining the physiological proliferation of granule neuron precursors (GNPs), and its …

Alternative splicing (AS) produces the different mRNA splicing bodies, which are then
translated into multiple protein isoforms and participate in various biological functions. With …

Linalool has outstanding antibacterial activity, while few studies have elucidated its
inhibitory mechanism based on omics combination techniques. This study aimed to …

Opinion statement Medulloblastoma is the most frequently diagnosed primary malignant
brain tumor among children. Currently available therapeutic strategies are based on surgical …

MYC-driven medulloblastoma is a major therapeutic challenge due to frequent metastasis
and a poor 5-year survival rate. MYC gene amplification results in transcriptional …

Aeromonas hydrophila is one of the main pathogens in aquaculture. Our previous studies
have shown that emodin could inhibit the proliferation of A. hydrophila, however, the …

Medulloblastoma (MB) is a clinically challenging, childhood brain tumor with a diverse
genetic makeup and differential miRNA profile. Aiming to identify deregulated miRNAs in …

MAP4K4 controlled integrin β1 activation and c-Met endocytosis are associated with invasive
behavior of medulloblastoma cells - PMC Back to Top Skip to main content NIH NLM Logo …

Medulloblastoma (MB), which originates from embryonic neural stem cells (NSCs) or neural
precursors in the developing cerebellum, is the most common malignant brain tumor of …

Dysregulation of repressor-element 1 silencing transcription factor REST/NRSF is related to
several neuropathies, including medulloblastoma, glioblastoma, Huntington's disease, and …