Neuroprotective phytochemicals in experimental ischemic stroke: mechanisms and potential clinical applications

H Xu, E Wang, F Chen, J Xiao… - Oxidative Medicine and …, 2021 - Wiley Online Library
Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …

[HTML][HTML] Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease

K Kumar, A Kumar, RM Keegan… - Biomedicine & …, 2018 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by
progressive deterioration of cognitive functions. The pathological hallmarks are extracellular …

[HTML][HTML] Comprehensive review of two groups of flavonoids in Carthamus tinctorius L.

B Xian, R Wang, H Jiang, Y Zhou, J Yan… - Biomedicine & …, 2022 - Elsevier
Safflower (Carthamus tinctorius L.) is cultivated in various countries for the flavonoid
compounds it contains. These flavonoids have been used in many industries as drugs …

Hydroxysafflor yellow A: a promising therapeutic agent for a broad spectrum of diseases

H Ao, W Feng, C Peng - Evidence‐Based Complementary and …, 2018 - Wiley Online Library
Hydroxysafflor yellow A (HSYA) is one of the major bioactive and water‐soluble compounds
isolated from Carthami Flos, the flower of safflower (Carthamus tinctorius L.). As a natural …

Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy

J Ye, S Lu, M Wang, W Ge, H Liu, Y Qi, J Fu… - Frontiers in …, 2020 - frontiersin.org
Myocardial ischemia/reperfusion (MI/R) injury is a serious threat to human health.
Hydroxysafflor yellow A (HSYA), the main water-soluble ingredient extracted from Carthami …

Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies

L Yu, Z Jin, M Li, H Liu, J Tao, C Xu, L Wang… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke, mostly caused by thromboembolic or thrombotic arterial occlusions, is a
primary leading cause of death worldwide with high morbidity and disability. Unfortunately …

Therapeutic potential of hydroxysafflor yellow A on cardio-cerebrovascular diseases

X Bai, WX Wang, RJ Fu, SJ Yue, H Gao… - Frontiers in …, 2020 - frontiersin.org
The incidence rate of cardio-cerebrovascular diseases (CCVDs) is increasing worldwide,
causing an increasingly serious public health burden. The pursuit of new promising …

Novel insight into the therapeutical potential of flavonoids from traditional Chinese medicine against cerebral ischemia/reperfusion injury

J Zhou, F Sun, W Zhang, Z Feng, Y Yang… - Frontiers in …, 2024 - frontiersin.org
Cerebral ischemia/reperfusion injury (CIRI) is a major contributor to poor prognosis of
ischemic stroke. Flavonoids are a broad family of plant polyphenols which are abundant in …

[HTML][HTML] Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial …

S Chen, M Sun, X Zhao, Z Yang… - Molecular …, 2019 - spandidos-publications.com
Stroke is the second most frequent cause of mortality, resulting in a huge societal burden
worldwide. Timely reperfusion is the most effective therapy; however, it is difficult to prevent …

Role of herbal teas in regulating cellular homeostasis and autophagy and their implications in regulating overall health

JM Brimson, MI Prasanth, DS Malar, R Sharika… - Nutrients, 2021 - mdpi.com
Tea is one of the most popular and widely consumed beverages worldwide, and possesses
numerous potential health benefits. Herbal teas are well-known to contain an abundance of …