The crosstalk between ferroptosis and cancer metastasis remains unclear. Here, we identify
AMER1 as a key regulator of ferroptosis. AMER1 loss causes resistance to ferroptosis in …

Abstract Bromodomain-Containing Protein 4 (BRD4) is a member of the BET family of
bromodomains, which participates in gene transcription process and is closely related to …

ATP-dependent chromatin remodeling by histone-modifying enzymes and chromatin
remodeling complexes is crucial for maintaining chromatin organization and facilitating gene …

Abstract Switch/sucrose-nonfermentable (SWI/SNF) chromatin-remodeling complexes are
critical regulators of chromatin dynamics during transcription, DNA replication, and DNA …

Bromodomain and extra-terminal domain (BET) proteins are epigenetic modulators that
regulate gene transcription through interacting with acetylated lysine residues of histone …

The glycolytic enzyme enolase 2 (ENO2) is dysregulated in many types of cancer. However,
the roles and detailed molecular mechanism of ENO2 in colorectal cancer (CRC) metastasis …

Abstract MIR4435-2HG, also known as LINC00978, has previously been described as an
oncogenic long noncoding RNA (lncRNA). However, we show here that Mir4435-2hg …

Our previous study demonstrated that tumor-suppressor circular RNAs (circRNAs) can be
specifically secreted outside of colorectal cancer (CRC) cells within exosomes to maintain …

Purpose: BRD9 is a defining component of the noncanonical SWI/SNF complex, which
regulates gene expression by controlling chromatin dynamics. Although recent studies have …

Abstract Microscopic plastic particles (0.1 µm–5 mm) are widespread hazardous pollutants,
and microfibres (MFs) are their dominant shape in habitats. Previous field and laboratory …