Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases

P Wu, X Zuo, H Deng, X Liu, L Liu, A Ji - Brain research bulletin, 2013 - Elsevier
Long noncoding RNAs (lncRNAs) have been attracting immense research interest, while
only a handful of lncRNAs have been characterized thoroughly. Their involvement in the …

Nitric oxide signaling in brain function, dysfunction, and dementia

JR Steinert, T Chernova, ID Forsythe - The Neuroscientist, 2010 - journals.sagepub.com
Nitric oxide (NO) is an important signaling molecule that is widely used in the nervous
system. With recognition of its roles in synaptic plasticity (long-term potentiation, LTP; long …

Non-coding RNAs with essential roles in neurodegenerative disorders

E Salta, B De Strooper - The Lancet Neurology, 2012 - thelancet.com
The importance of various classes of regulatory non-protein-coding RNA molecules
(ncRNAs) in the normal functioning of the CNS is becoming increasingly evident. ncRNAs …

Eukaryotic regulatory RNAs: an answer to the 'genome complexity'conundrum

KV Prasanth, DL Spector - Genes & development, 2007 - genesdev.cshlp.org
A large portion of the eukaryotic genome is transcribed as noncoding RNAs (ncRNAs).
While once thought of primarily as “junk,” recent studies indicate that a large number of …

Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease

MF Mehler, JS Mattick - Physiological reviews, 2007 - journals.physiology.org
The progressive maturation and functional plasticity of the nervous system in health and
disease involve a dynamic interplay between the transcriptome and the environment. There …

Lymnaea stagnalis as model for translational neuroscience research: From pond to bench

V Rivi, C Benatti, C Colliva, G Radighieri… - Neuroscience & …, 2020 - Elsevier
The purpose of this review is to illustrate how a reductionistic, but sophisticated, approach
based on the use of a simple model system such as the pond snail Lymnaea stagnalis (L …

Evolution of the nitric oxide synthase family in metazoans

N Andreakis, S D'Aniello, R Albalat… - Molecular Biology …, 2011 - academic.oup.com
Nitric oxide (NO) is essential to many physiological functions and operates in several
signaling pathways. It is not understood how and when the different isoforms of nitric oxide …

Mechanisms and immunological roles of apoptosis in molluscs

K Terahara, KG Takahashi - Current pharmaceutical design, 2008 - ingentaconnect.com
Molluscan defense mechanisms are regulated to innate immunity, which is largely
dependent on cellular components such as hemocytes possessing phagocytic and …

The ambiguous boundary between genes and pseudogenes: the dead rise up, or do they?

D Zheng, MB Gerstein - Trends in Genetics, 2007 - cell.com
Pseudogenes have long been considered to be 'dead', nonfunctional by-products of
genome evolution. However, several lines of evidence now show that some pseudogenes …

Nitric oxide in marine invertebrates: a comparative perspective

A Palumbo - Comparative Biochemistry and Physiology Part A …, 2005 - Elsevier
Since the discovery of the biological effects of nitric oxide (NO) more than two decades ago,
NO has been identified as an important physiological modulator and a messenger molecule …