Synovial sarcoma
C Fisher - Annals of diagnostic pathology, 1998 - Elsevier
Synovial sarcoma is a rare soft tissue tumor of children and adults that is unrelated to
synovium and can occur in almost any part of the body. The familiar biphasic synovial …
synovium and can occur in almost any part of the body. The familiar biphasic synovial …
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. Synovial sarcoma
AA Sandberg, JA Bridge - Cancer genetics and cytogenetics, 2002 - Elsevier
The present Update on synovial sarcoma (SS) follows the pattern of previous ones in that it
presents findings related to this tumor which have appeared since 1994 when our book was …
presents findings related to this tumor which have appeared since 1994 when our book was …
[HTML][HTML] Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma
C Kadoch, GR Crabtree - Cell, 2013 - cell.com
Recent exon sequencing studies have revealed that over 20% of human tumors have
mutations in subunits of mSWI/SNF (BAF) complexes. To investigate the underlying …
mutations in subunits of mSWI/SNF (BAF) complexes. To investigate the underlying …
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
J Clark, PJ Rocques, AJ Crew, S Gill, J Shipley… - Nature …, 1994 - nature.com
Human synovial sarcomas contain a recurrent and specific chromosomal translocation t (X;
18)(p11. 2; q11. 2). By screening a synovial sarcoma cDNA library with a yeast artificial …
18)(p11. 2; q11. 2). By screening a synovial sarcoma cDNA library with a yeast artificial …
SYT–SSX Gene Fusion as a Determinant of Morphology and Prognosis in Synovial Sarcoma
A Kawai, J Woodruff, JH Healey… - … England Journal of …, 1998 - Mass Medical Soc
Background Synovial sarcomas account for up to 10 percent of soft-tissue sarcomas and
include two major histologic subtypes, biphasic and monophasic, defined respectively by the …
include two major histologic subtypes, biphasic and monophasic, defined respectively by the …
Immunohistochemical analysis of NY‐ESO‐1 antigen expression in normal and malignant human tissues
AA Jungbluth, YT Chen, E Stockert… - … Journal of Cancer, 2001 - Wiley Online Library
Abstract NY‐ESO‐1, a member of the CT (cancer/testis) family of antigens, is expressed in
normal testis and in a range of human tumor types. Knowledge of NY‐ESO‐1 expression …
normal testis and in a range of human tumor types. Knowledge of NY‐ESO‐1 expression …
Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel‐associated box in human synovial sarcoma.
AJ Crew, J Clark, C Fisher, S Gill, R Grimer… - The EMBO …, 1995 - embopress.org
We demonstrate that the cytogenetically defined translocation t (X; 18)(p11. 2; q11. 2) found
in human synovial sarcoma results in the fusion of the chromosome 18 SYT gene to either of …
in human synovial sarcoma results in the fusion of the chromosome 18 SYT gene to either of …
Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors
JI Koontz, AL Soreng, M Nucci… - Proceedings of the …, 2001 - National Acad Sciences
Endometrial stromal tumors are divided into three types: benign stromal nodules,
endometrial stromal sarcomas, and undifferentiated endometrial sarcomas. A variety of …
endometrial stromal sarcomas, and undifferentiated endometrial sarcomas. A variety of …
Monophasic and biphasic synovial sarcomas abundantly express cancer/testis antigen NY‐ESO‐1 but not MAGE‐A1 or CT7
AA Jungbluth, CR Antonescu, KJ Busam… - … journal of cancer, 2001 - Wiley Online Library
Synovial sarcomas are high‐grade malignant mesenchymal tumors with biphasic (BSS) and
monophasic (MSS) variants that carry a pathognomonic cytogenetic alteration, t (X; 18) …
monophasic (MSS) variants that carry a pathognomonic cytogenetic alteration, t (X; 18) …
Molecular mechanisms underlying human synovial sarcoma development
NR dos Santos, DRH de Bruijn… - Genes, Chromosomes …, 2001 - Wiley Online Library
Synovial sarcomas are rather common among soft‐tissue tumors, occurring at any age but
affecting mainly young adults. The vast majority of synovial sarcomas carries at (X; 18)(p11 …
affecting mainly young adults. The vast majority of synovial sarcomas carries at (X; 18)(p11 …