This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

Proper tissue function and regeneration rely on robust spatial and temporal control of
biophysical and biochemical microenvironmental cues through mechanisms that remain …

Harnessing the ability to precisely and reproducibly actuate fluids and manipulate
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …

Developing biologically relevant models of human tissues and organs is an important
enabling step for disease modeling and drug discovery. Recent advances in tissue …

A hallmark of Parkinson's disease is the progressive loss of nigrostriatal dopaminergic
neurons. We derived human neuroepithelial cells from induced pluripotent stem cells and …

The advent of stem cell based therapies has brought regenerative medicine into an
increased focus as a part of the modern medicine practice, with a potential to treat a myriad …

Abstract Organ‐on‐chip (OOC) platforms have attracted attentions of pharmaceutical
companies as powerful tools for screening of existing drugs and development of new drug …

In the past two decades, Micro Fluidic Systems (MFS) have emerged as a powerful tool for
biosensing, particularly in enriching and purifying molecules and cells in biological samples …

Hydrogels in which cells are encapsulated are of great potential interest for tissue
engineering applications. These gels provide a structure inside which cells can spread and …

Stem cells always balance between self‐renewal and differentiation. Hence, stem cell
culture parameters are critical and need to be continuously refined according to progress in …