Update of standard practices for new method validation in forensic toxicology

SMR Wille, W Coucke, T De Baere… - Current Pharmaceutical …, 2017 - ingentaconnect.com
International agreement concerning validation guidelines is important to obtain quality
forensic bioanalytical research and routine applications as it all starts with the reporting of …

Aspects of matrix effects in applications of liquid chromatography–mass spectrometry to forensic and clinical toxicology—a review

FT Peters, D Remane - Analytical and Bioanalytical Chemistry, 2012 - Springer
In the last decade, liquid chromatography coupled to (tandem) mass spectrometry (LC–MS
(− MS)) has become a versatile technique with many routine applications in clinical and …

Development and validation of a liquid chromatography–tandem mass spectrometry method for the quantitation of synthetic cannabinoids of the aminoalkylindole type …

S Dresen, S Kneisel, W Weinmann… - Journal of mass …, 2011 - Wiley Online Library
After the discovery of synthetic cannabimimetic substances in 'Spice'‐like herbal mixtures
marketed as 'incense'or 'plant fertilizer'the active compounds have been declared as …

Synthetic cannabinoids: analysis and metabolites

MA ElSohly, W Gul, AS Wanas, MM Radwan - Life sciences, 2014 - Elsevier
Cannabimimetics (commonly referred to as synthetic cannabinoids), a group of compounds
encompassing a wide range of chemical structures, have been developed by scientists with …

Analysis of 30 synthetic cannabinoids in serum by liquid chromatography‐electrospray ionization tandem mass spectrometry after liquid‐liquid extraction

S Kneisel, V Auwärter - Journal of mass spectrometry, 2012 - Wiley Online Library
The analysis of synthetic cannabinoids in human matrices is of particular importance in the
fields of forensic and clinical toxicology since cannabis users partly shift to the consumption …

Ion suppression and enhancement effects of co‐eluting analytes in multi‐analyte approaches: systematic investigation using ultra‐high‐performance liquid …

D Remane, MR Meyer, DK Wissenbach… - … in Mass Spectrometry, 2010 - Wiley Online Library
In multi‐analyte procedures, sufficient separation is important to avoid interferences,
particularly when using liquid chromatography/mass spectrometry (LC/MS) because of …

Activity-based detection of consumption of synthetic cannabinoids in authentic urine samples using a stable cannabinoid reporter system

A Cannaert, F Franz, V Auwärter… - Analytical chemistry, 2017 - ACS Publications
Synthetic cannabinoids (SCs) continue to be the largest group of new psychoactive
substances (NPS) monitored by the European Monitoring Center of Drugs and Drugs of …

Quantification of (9R)‐ and (9S)‐hexahydrocannabinol (HHC) via GC–MS in serum/plasma samples from drivers suspected of cannabis consumption and …

L Höfert, S Becker, J Dreßler… - Drug testing and …, 2024 - Wiley Online Library
The semisynthetic cannabinoid hexahydrocannabinol (HHC) is currently getting a lot of
media attention because the legal status in many countries is not clearly specified. In this …

Characterization of the designer benzodiazepine diclazepam and preliminary data on its metabolism and pharmacokinetics

B Moosmann, P Bisel, V Auwärter - Drug Testing and Analysis, 2014 - Wiley Online Library
Designer benzodiazepines, first offered in online shops selling 'research chemicals' in 2012,
provide an attractive alternative to prescription‐only benzodiazepines as they are readily …

Analysis of 30 synthetic cannabinoids in oral fluid using liquid chromatography‐electrospray ionization tandem mass spectrometry

S Kneisel, V Auwärter, J Kempf - Drug testing and analysis, 2013 - Wiley Online Library
In recent years, the analysis of synthetic cannabinoids in human specimens has gained
enormous importance in the broad field of drug testing. Nevertheless, the considerable …