Current status of matrix-assisted laser desorption/ionization–time-of-flight mass spectrometry (MALDI-TOF MS) in clinical diagnostic microbiology
S Tsuchida, H Umemura, T Nakayama - Molecules, 2020 - mdpi.com
Mass spectrometry (MS), a core technology for proteomics and metabolomics, is currently
being developed for clinical applications. The identification of microorganisms in clinical …
being developed for clinical applications. The identification of microorganisms in clinical …
[HTML][HTML] After another decade: LC–MS/MS became routine in clinical diagnostics
C Seger, L Salzmann - Clinical biochemistry, 2020 - Elsevier
Tandem mass spectrometry–especially in combination with liquid chromatography (LC–
MS/MS)–is applied in a multitude of important diagnostic niches of laboratory medicine. It is …
MS/MS)–is applied in a multitude of important diagnostic niches of laboratory medicine. It is …
[HTML][HTML] Identification and characterization of post-translational modifications: Clinical implications
J Hermann, L Schurgers, V Jankowski - Molecular aspects of medicine, 2022 - Elsevier
Post-translational modifications (PTMs) generate marginally modified isoforms of native
peptides, proteins and lipoproteins thereby regulating protein functions, molecular …
peptides, proteins and lipoproteins thereby regulating protein functions, molecular …
Global chemical analysis of biology by mass spectrometry
Mass spectrometry instruments measure the mass to charge ratio of ions, from which we
infer the molecular structures. They are key tools for investigating the incredibly diverse …
infer the molecular structures. They are key tools for investigating the incredibly diverse …
Glycosylation of immunoglobulin G associates with clinical features of inflammatory bowel diseases
Background and Aims Causes of inflammatory bowel diseases are not well understood and
the most prominent forms, Crohn's disease (CD) and ulcerative colitis (UC), are sometimes …
the most prominent forms, Crohn's disease (CD) and ulcerative colitis (UC), are sometimes …
Recent advances in on-site mass spectrometry analysis for clinical applications
In recent years, mass spectrometry (MS) is increasingly attracting interests for clinical
applications, which also calls for technical innovations to make a transfer of MS from …
applications, which also calls for technical innovations to make a transfer of MS from …
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories
AG Birhanu - Clinical Proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …
Theranostic cells: emerging clinical applications of synthetic biology
Synthetic biology seeks to redesign biological systems to perform novel functions in a
predictable manner. Recent advances in bacterial and mammalian cell engineering include …
predictable manner. Recent advances in bacterial and mammalian cell engineering include …
Key questions about the future of laboratory medicine in the next decade of the 21st century: a report from the IFCC-Emerging Technologies Division
RF Greaves, S Bernardini, M Ferrari, P Fortina… - Clinica Chimica …, 2019 - Elsevier
This review advances the discussion about the future of laboratory medicine in the 2020s. In
five major topic areas: 1. the “big picture” of healthcare; 2. pre-analytical factors; 3. Analytical …
five major topic areas: 1. the “big picture” of healthcare; 2. pre-analytical factors; 3. Analytical …
Comprehensive subspecies identification of 175 nontuberculous mycobacteria species based on 7547 genomic profiles
Y Matsumoto, T Kinjo, D Motooka… - Emerging microbes & …, 2019 - Taylor & Francis
The prevalence of nontuberculous mycobacteria (NTM) pulmonary diseases has been
increasing worldwide. NTM consist of approximately 200 species and distinguishing …
increasing worldwide. NTM consist of approximately 200 species and distinguishing …