Mass spectrometry (MS), a core technology for proteomics and metabolomics, is currently
being developed for clinical applications. The identification of microorganisms in clinical …

Tandem mass spectrometry–especially in combination with liquid chromatography (LC–
MS/MS)–is applied in a multitude of important diagnostic niches of laboratory medicine. It is …

Post-translational modifications (PTMs) generate marginally modified isoforms of native
peptides, proteins and lipoproteins thereby regulating protein functions, molecular …

Mass spectrometry instruments measure the mass to charge ratio of ions, from which we
infer the molecular structures. They are key tools for investigating the incredibly diverse …

Background and Aims Causes of inflammatory bowel diseases are not well understood and
the most prominent forms, Crohn's disease (CD) and ulcerative colitis (UC), are sometimes …

In recent years, mass spectrometry (MS) is increasingly attracting interests for clinical
applications, which also calls for technical innovations to make a transfer of MS from …

Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …

Synthetic biology seeks to redesign biological systems to perform novel functions in a
predictable manner. Recent advances in bacterial and mammalian cell engineering include …

This review advances the discussion about the future of laboratory medicine in the 2020s. In
five major topic areas: 1. the “big picture” of healthcare; 2. pre-analytical factors; 3. Analytical …

The prevalence of nontuberculous mycobacteria (NTM) pulmonary diseases has been
increasing worldwide. NTM consist of approximately 200 species and distinguishing …