The development of new nanomaterials with high biomedical performance and low toxicity is
essential to obtain more efficient therapy and precise diagnostic tools and devices. Recently …

As life expectancy increases, malfunction or loss of tissue caused by injury or disease leads
to reduced quality of life in many patients at significant socioeconomic cost. Even though …

Reconstruction of large bone defects remains problematic in orthopedic and craniofacial
clinical practice. Autografts are limited in supply and are associated with donor site morbidity …

Natural biomaterials such as collagen show promise in tissue engineering applications due
to their inherent bioactivity. The main limitation of collagen is its low mechanical strength and …

Porous scaffolds were engineered from refibrillized collagen of the jellyfish Rhopilema
esculentum for potential application in cartilage regeneration. The influence of collagen …

Gene therapy involves the introduction of foreign genetic material into cells in order exert a
therapeutic effect. The application of gene therapy to the field of orthopaedic tissue …

Tissue engineering and nanotechnology have enabled engineering of nanostructured
materials to meet the current challenges in bone treatment owing to rising occurrence of …

Hydroxypropyltrimethyl ammonium chloride chitosan (HACC) was synthesised with differing
degrees of substitution (6%, 18% and 44%) of quaternary ammonium by reacting chitosan …

Patients with osteoporosis are more likely to suffer prosthesis displacement, subsidence or
periprosthesis fracture after prosthesis replacement. This is due to excessive osteoclast …

Nanofiber poly (ε-caprolactone)(PCL) scaffolds were fabricated by electrospinning, and their
ability to enhance the osteoblastic behavior of marrow stromal cells (MSCs) in osteogenic …