Regulation of the NLRP3 inflammasome with natural products against chemical-induced liver injury

J Zou, SP Wang, YT Wang, JB Wan - Pharmacological research, 2021 - Elsevier
The past decades have witnessed significant progress in understanding the process of
sterile inflammation, which is dependent on a cytosolic complex termed the nucleotide …

Magnolol: Chemistry and biology

J Xu, H Xu - Industrial Crops and Products, 2023 - Elsevier
Magnolol is a conventional polyphenolic bioactive substance extracted and isolated from the
stem bark of the Magnoliaceae plant Magnolia officinalis Rehd. et Wils. It exhibited a wide …

Echinacea purpurea polysaccharide prepared by fractional precipitation prevents alcoholic liver injury in mice by protecting the intestinal barrier and regulating liver …

W Jiang, H Zhu, W Xu, C Liu, B Hu, Y Guo… - International Journal of …, 2021 - Elsevier
Oxidative damage and intestinal dysbiosis are regarded as crucial culprits in alcoholic liver
disease (ALD). This study aimed to examine the protective effects of Echinacea purpurea …

Curcumin and Baicalin ameliorate ethanol‐induced liver oxidative damage via the Nrf2/HO‐1 pathway

X Wang, X Chang, H Zhan, Q Zhang… - Journal of Food …, 2020 - Wiley Online Library
One of the key mechanisms of alcoholic liver disease is oxidative stress. Both Curcumin and
Baicalin exert antioxidant effects, but the mechanism of their combined effects of ethanol …

Scutellarin prevents acute alcohol-induced liver injury via inhibiting oxidative stress by regulating the Nrf2/HO-1 pathway and inhibiting inflammation by regulating the …

X Zhang, Z Dong, H Fan, Q Yang, G Yu, E Pan… - Journal of Zhejiang …, 2023 - Springer
Alcoholic liver disease (ALD) is the most frequent liver disease worldwide, resulting in
severe harm to personal health and posing a serious burden to public health. Based on the …

Sinomenine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress, inflammation and apoptosis in mice

H Fan, T Tu, X Zhang, Q Yang, G Liu, T Zhang… - Food and Chemical …, 2022 - Elsevier
Acute liver injury (ALI) is a common pathology of liver diseases caused by different kinds of
pathogenic factors including viral infection, alcohol intake, drugs, and chemical poisons …

Magnolol effectively ameliorates diabetic peripheral neuropathy in mice

J Yang, Y Wei, T Zhao, X Li, X Zhao, X Ouyang, L Zhou… - Phytomedicine, 2022 - Elsevier
Background Diabetic peripheral neuropathy (DPN) is a common complication of diabetes
lacking efficient treatment. Magnolol (MG), a peroxisome proliferator-activated receptor γ …

[HTML][HTML] The effects of magnolol supplementation on growth performance, meat quality, oxidative capacity, and intestinal microbiota in broilers

Q Xie, K Xie, J Yi, Z Song, H Zhang, X He - Poultry Science, 2022 - Elsevier
The aim of the present study was to evaluate the effect of magnolol (MAG) on growth
performance, meat quality, oxidative capacity, and intestinal microbiota in the yellow-feather …

Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-κB and HO-1 signaling pathways in mice

D Wu, S Li, X Liu, J Xu, A Jiang, Y Zhang, Z Liu… - International …, 2020 - Elsevier
Allergic asthma is the most common type of asthma which characterized by inflammatory
responses of the airways. Alpinetin, a flavonoid compound derived from the ginger family of …

Empagliflozin ameliorates ethanol-induced liver injury by modulating NF-κB/Nrf-2/PPAR-γ interplay in mice

AM Abdelhamid, AR Elsheakh, RR Abdelaziz… - Life sciences, 2020 - Elsevier
Background Excessive alcohol intake contributes to severe liver damage involving oxidative
stress and inflammatory responses, which make them promising therapeutic targets …