Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

Focal adhesion dynamics in cellular function and disease

YG Mishra, B Manavathi - Cellular signalling, 2021 - Elsevier
Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

[HTML][HTML] Extracellular matrix-based biomaterials for cardiovascular tissue engineering

A Khanna, M Zamani, NF Huang - Journal of cardiovascular development …, 2021 - mdpi.com
Regenerative medicine and tissue engineering strategies have made remarkable progress
in remodeling, replacing, and regenerating damaged cardiovascular tissues. The design of …

[HTML][HTML] Stimuli-responsive materials: A smart way to study dynamic cell responses

M Bril, S Fredrich, NA Kurniawan - Smart Materials in Medicine, 2022 - Elsevier
Cells in the body reside within the extracellular matrix (ECM), a three-dimensional
environment that not only provides structural support for the cells, but also influences cellular …

[HTML][HTML] The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction

DGS Wilson, A Tinker, T Iskratsch - Communications Biology, 2022 - nature.com
Dystrophin is the central protein of the dystrophin-glycoprotein complex (DGC) in skeletal
and heart muscle cells. Dystrophin connects the actin cytoskeleton to the extracellular matrix …

[HTML][HTML] A guide to functionalisation and bioconjugation strategies to surface-initiated polymer brushes

CE Neri-Cruz, FME Teixeira, JE Gautrot - Chemical Communications, 2023 - pubs.rsc.org
Since the first introduction of their concept in the 1980s and 90s, polymer brushes have
been the focus of intense research efforts to identify novel physico-chemical properties and …

Advances in design of polymer brush functionalized inorganic nanomaterials and their applications in biomedical arena

S Dutta, N Shreyash, BK Satapathy… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Grafting of polymer brush (assembly of polymer chains tethered to the substrate by one end)
is emerging as one of the most viable approach to alter the surface of inorganic …

Biofunctionalized patterned polymer brushes via thiol–ene coupling for the control of cell adhesion and the formation of cell arrays

B Colak, S Di Cio, JE Gautrot - Biomacromolecules, 2018 - ACS Publications
Thiol–ene radical coupling is increasingly used for the biofunctionalization of biomaterials.
Thiol–ene chemistry presents interesting features that are particularly attractive for platforms …

Highly stable RNA capture by dense cationic polymer brushes for the design of cytocompatible, serum-stable siRNA delivery vectors

D Li, AS Sharili, J Connelly, JE Gautrot - Biomacromolecules, 2018 - ACS Publications
The high density of polymer brushes confers to these coatings unique physicochemical
properties, in particular for the regulation of biomolecular interaction and the design of highly …

Wool Keratin Nanoparticle-Based Micropatterns for Cellular Guidance Applications

DJ Trojanowska, G Suarato, C Braccia… - ACS Applied Nano …, 2022 - ACS Publications
The waste stream of low-grade wool is an underutilized source of keratin-rich materials with
appropriate methods for upcycling into high value-added products still being an open …