Early atherosclerosis features functional and structural changes in the endothelial barrier
function that affect the traffic of molecules and solutes between the vessel lumen and the …

The generation of reactive oxygen species (ROS) plays an important role for the
maintenance of cellular processes and functions in the body. However, the excessive …

Summary Caveolae, ALK1 and SR-B1 are identified as key regulators in the LDL
transcytosis across the endothelium. Endothelial LDL transcytosis might be a potential …

Caveolae are 50–100 nm cell surface plasma membrane invaginations observed in
terminally differentiated cells. They are characterized by the presence of the protein marker …

Context Previous studies have highlighted significant therapeutic effects of Qiqilian (QQL)
capsule on hypertension in spontaneously hypertensive rats (SHRs); however, its …

Scavenger receptor type BI (SR‐BI), the major receptor for high‐density lipoprotein (HDL)
mediates the delivery of cholesterol ester and cholesterol from HDL to the cell membrane …

Azilsartan is the eighth approved member of angiotensin II receptor blockers for
hypertension treatment. Considering that some drugs have additional effects when …

Two important brown algae, Sargassum horneri and Sargassum thunbergii are widely
distributed along the coastal line of China. In this study, antioxidant, angiotensin-converting …

Elevated plasma low density lipoprotein (LDL) is an established risk factor for cardiovascular
disease. In addition to being able to cross the endothelial barrier to become accumulated in …

ABSTRACT Background: Signal transduction of Angiotensin II (Ang II) induced autophagy
and its role in Ang II–induced dysfunction of HUVECs are still unclear. Methods: HUVECs …