[HTML][HTML] Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction
AKL Chen, S Reuveny, SKW Oh - Biotechnology advances, 2013 - Elsevier
Mesenchymal stem cells (MSCs) have recently made significant progress with multiple
clinical trials targeting modulation of immune responses, regeneration of bone, cartilage …
clinical trials targeting modulation of immune responses, regeneration of bone, cartilage …
[HTML][HTML] Progress and challenges in large-scale expansion of human pluripotent stem cells
C Kropp, D Massai, R Zweigerdt - Process Biochemistry, 2017 - Elsevier
The constant supply of high cell numbers generated by defined, robust, and economically
viable culture processes is indispensable for the envisioned application of human …
viable culture processes is indispensable for the envisioned application of human …
A scalable system for production of functional pancreatic progenitors from human embryonic stem cells
TC Schulz, HY Young, AD Agulnick, MJ Babin… - PloS one, 2012 - journals.plos.org
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will
require the translation of proof-of-principle concepts into a scalable, controlled, and …
require the translation of proof-of-principle concepts into a scalable, controlled, and …
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
Y Lei, DV Schaffer - … of the National Academy of Sciences, 2013 - National Acad Sciences
Human pluripotent stem cells (hPSCs), including human embryonic stem cells and induced
pluripotent stem cells, are promising for numerous biomedical applications, such as cell …
pluripotent stem cells, are promising for numerous biomedical applications, such as cell …
Process engineering of human pluripotent stem cells for clinical application
Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture
H Kempf, R Olmer, C Kropp, M Rückert, M Jara-Avaca… - Stem cell reports, 2014 - cell.com
To harness the potential of human pluripotent stem cells (hPSCs), an abundant supply of
their progenies is required. Here, hPSC expansion as matrix-independent aggregates in …
their progenies is required. Here, hPSC expansion as matrix-independent aggregates in …
The use of nanofibrillar cellulose hydrogel as a flexible three-dimensional model to culture human pluripotent stem cells
YR Lou, L Kanninen, T Kuisma, J Niklander… - Stem cells and …, 2014 - liebertpub.com
Human embryonic stem cells and induced pluripotent stem cells have great potential in
research and therapies. The current in vitro culture systems for human pluripotent stem cells …
research and therapies. The current in vitro culture systems for human pluripotent stem cells …
Concise review: the evolution of human pluripotent stem cell culture: from feeder cells to synthetic coatings
Current practices to maintain human pluripotent stem cells (hPSCs), which include induced
pluripotent stem cells and embryonic stem cells, in an undifferentiated state typically depend …
pluripotent stem cells and embryonic stem cells, in an undifferentiated state typically depend …
Scalable expansion of human pluripotent stem cells in suspension culture
Routine commercial and clinical applications of human pluripotent stem cells (hPSCs) and
their progenies will require increasing cell quantities that cannot be provided by …
their progenies will require increasing cell quantities that cannot be provided by …
[HTML][HTML] Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells
VC Chen, J Ye, P Shukla, G Hua, D Chen, Z Lin, J Liu… - Stem cell …, 2015 - Elsevier
To meet the need of a large quantity of hPSC-derived cardiomyocytes (CM) for pre-clinical
and clinical studies, a robust and scalable differentiation system for CM production is …
and clinical studies, a robust and scalable differentiation system for CM production is …