[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …
deaths in westernized societies with numbers increasing at a marked rate in developing …
Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy
JE McLaren, DR Michael, TG Ashlin, DP Ramji - Progress in lipid research, 2011 - Elsevier
Cardiovascular disease is the biggest killer globally and the principal contributing factor to
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways
Inflammation is set off when innate immune cells detect infection or tissue injury. Tight
control of the severity, duration, and location of inflammation is an absolute requirement for …
control of the severity, duration, and location of inflammation is an absolute requirement for …
Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets
Atherosclerosis, the primary cause of cardiovascular disease (CVD), is a chronic
inflammatory disorder in the walls of medium and large arteries. CVD is currently …
inflammatory disorder in the walls of medium and large arteries. CVD is currently …
Atherosclerosis and interferon-γ: new insights and therapeutic targets
I Voloshyna, MJ Littlefield, AB Reiss - Trends in cardiovascular medicine, 2014 - Elsevier
Atherosclerosis is considered to be a chronic inflammatory disease of the arterial wall.
Atherogenesis is accompanied by local production and release of inflammatory mediators …
Atherogenesis is accompanied by local production and release of inflammatory mediators …
[HTML][HTML] Lithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor
TWH Pols, T Puchner, HI Korkmaz, M Vos… - PLoS …, 2017 - journals.plos.org
Bile acids are established signaling molecules next to their role in the intestinal
emulsification and uptake of lipids. We here aimed to identify a potential interaction between …
emulsification and uptake of lipids. We here aimed to identify a potential interaction between …
Exercise mimetics and JAK inhibition attenuate IFN-γ–induced wasting in engineered human skeletal muscle
Chronic inflammatory diseases often lead to muscle wasting and contractile deficit. While
exercise can have anti-inflammatory effects, the underlying mechanisms remain unclear …
exercise can have anti-inflammatory effects, the underlying mechanisms remain unclear …
[HTML][HTML] The influence of dysfunctional signaling and lipid homeostasis in mediating the inflammatory responses during atherosclerosis
ML Buckley, DP Ramji - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Atherosclerosis, the underlying cause of myocardial infarction and thrombotic
cerebrovascular events, is responsible for the majority of deaths in westernized societies …
cerebrovascular events, is responsible for the majority of deaths in westernized societies …
[HTML][HTML] Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in …
W Sheng, Y Zong, A Mohammad, D Ajit, J Cui… - Journal of …, 2011 - Springer
Background Activation of glial cells, including astrocytes and microglia, has been implicated
in the inflammatory responses underlying brain injury and neurodegenerative diseases …
in the inflammatory responses underlying brain injury and neurodegenerative diseases …
Proteomic Quantification and Site-Mapping of S-Nitrosylated Proteins Using Isobaric iodoTMT Reagents
Z Qu, F Meng, RD Bomgarden, RI Viner… - Journal of proteome …, 2014 - ACS Publications
S-Nitrosylation is a redox-based protein post-translational modification in response to nitric
oxide signaling and is involved in a wide range of biological processes. Detection and …
oxide signaling and is involved in a wide range of biological processes. Detection and …