Targeting the gut–eye axis: An emerging strategy to face ocular diseases

LIM Campagnoli, A Varesi, A Barbieri… - International Journal of …, 2023 - mdpi.com
The human microbiota refers to a large variety of microorganisms (bacteria, viruses, and
fungi) that live in different human body sites, including the gut, oral cavity, skin, and eyes. In …

Next generation probiotics: Engineering live biotherapeutics

SK Murali, TJ Mansell - Biotechnology Advances, 2024 - Elsevier
The population dynamics of the human microbiome have been associated with inflammatory
bowel disease, cancer, obesity, autoimmune diseases, and many other human disease …

[HTML][HTML] Comparing and Contrasting the Effects of the SGLT Inhibitors Canagliflozin and Empagliflozin on the Progression of Retinopathy

LY Herat, JR Matthews, EP Rakoczy… - Frontiers in Bioscience …, 2023 - imrpress.com
Background: Diabetic retinopathy (DR) is a leading cause of end-stage blindness globally
and is arguably one of the most disabling complications of both Type 1 and Type 2 diabetes …

Research progress of diabetic retinopathy and gut microecology

R Wang, QY Wang, Y Bai, YG Bi, SJ Cai - Frontiers in microbiology, 2023 - frontiersin.org
According to the prediction of the International Diabetes Federation, global diabetes mellitus
(DM) patients will reach 783.2 million in 2045. The increasing incidence of DM has led to a …

[HTML][HTML] Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock …

X Mei, B Mell, S Aryal, I Manandhar, R Tummala… - Pharmacological …, 2023 - Elsevier
Engineered gut microbiota represents a new frontier in medicine, in part serving as a vehicle
for the delivery of therapeutic biologics to treat a range of host conditions. The gut microbiota …

Unveiling the gut-eye axis: how microbial metabolites influence ocular health and disease

Y Nguyen, J Rudd Zhong Manis… - Frontiers in …, 2024 - frontiersin.org
The intricate interplay between the gut microbiota and ocular health has surpassed
conventional medical beliefs, fundamentally reshaping our understanding of organ …