Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …

The myocardium behaves like a sophisticated orchestra that expresses its true potential only
if each member performs the correct task harmonically. Recapitulating its complexity within …

Heart failure is a global problem with an estimated prevalence of 38 million patients
worldwide, a number that is increasing with the ageing of the population. It is the most …

Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …

Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …

Exosomes are the most extensively characterized class of secreted membrane vesicles that
carry proteins and RNAs for intercellular communication. They are increasingly seen as …

Mesenchymal stem cells (MSCs) are multipotent cells found in several adult tissues.
Transplanted allogeneic MSCs can be detected in recipients at extended time points …